Devon Witherspoon had his first interception Monday night, and he made it count.

Kyle Shanahan and Nick Bosa weigh in on the MVP chatter surrounding 49ers running back Christian McCaffrey.

The Seahawks quarterback missed the final 3:05 of the first half to have his knee examined.

Brock Purdy joined elite company with his spectacular performance in Sunday's win over the Arizona Cardinals.

NBC Sports Bay Area's Jennifer Lee Chan dives into the PFF grades from the 49ers' win over the Cardinals in Week 4.

Christian McCaffrey is putting up historic numbers through four games this season, making it even harder for Kyle Shanahan to take him out of the game.

The Seahawks quarterback left for the training room in the second quarter to be evaluated.

Geno Smith wasn't happy with the Giants defense on Monday night.

Here are 13 stats showing all the ways Christian McCaffrey etched his name into NFL and 49ers history in Week 4.

Tom E. Curran and Marc Bertrand react to the Patriots' 38-3 loss to the Cowboys and what it says about where this team is in the post-Tom Brady era.

The Giants and Seahawks combined for three punts, three accepted penalties, 103 yards, seven first downs and a lost fumble in the first quarter.

Most of the time in the sports world, it only feels like forever since the last time a team experienced a joyous moment, but in the case of the Chicago Bears, it really has been a long, long wait. The Bears are not just 0-4 on the 2023 season, but they also lost their final 10 games of the 2022 campaign...

After Sunday's overtime victory over the Colts, Rams quarterback Matthew Stafford said he'll play on Sunday, against the Eagles.

Conditions weren't ideal for Mike McDaniel, Tua Tagovailoa and Miami to execute on Sunday in one particular way. That can serve as valuable information going forward.

Promising young Patriots cornerback Christian Gonzalez suffered a shoulder injury against the Cowboys, and an initial report on his outlook doesn't look good.

The 49ers' offensive line is preparing for a difficult challenge against Micah Parsons and the Cowboys.

The Rams say Matthew Stafford's hip injury shouldn't even keep him out of practice and should play against Eagles. Cooper Kupp will practice this week.

Rams quarterback Matthew Stafford suffered a hip injury during Sunday's overtime thriller in Indy.

Rams rookie Puka Nacua reached the locker room just as coach Sean McVay awarded him the game ball for catching the game-winning touchdown against the Colts.

Here's what you need to know about how to watch Monday Night Football.

The Steelers waived receiver Dez Fitzpatrick on Monday, the team announced.

A running back hasn't won the NFL MVP since 2012, but NBC Sports Bay Area's Donte Whitner is convinced that will end this season.

Rex Ryan couldn't pass up an opportunity to rip Patriots QB Mac Jones after his brutal performance against the Cowboys.

Nick Sirianni on Monday said right guard Cam Jurgens is "week-to-week" with a foot injury suffered in the second quarter against the Commanders.

One of the beautiful aspects of professional sports is that hitting rock bottom comes with a hefty consolation prize. This was the case last season for the Chicago Bears, who acquired the No. 1 overall draft pick by finishing the season with the NFL's worst record. Unfortunately, the fruits of that pick and the team's massive offseason free-agent haul have...

Philadelphia Eagles head coach Nick Sirianni defended two calls late vs. Washington that could've cost the team. By Reuben Frank

On Sunday, the Broncos lost running back Javonte Williams to a hip injury.

Bills cornerback Tre'Davious White has torn his Achilles and will be out for the rest of the season, Bills head coach Sean McDermott confirmed in his Monday press conference.

The Bears announced they designated starting left guard Teven Jenkins to return to practice on Monday. It was a welcome bit of good news amidst the whirlwind of drama that continues to swirl around the team. Jenkins began the season on injured reserve with a leg injury, which forced the Bears to move Cody Whitehair from center to left guard....

Cowboys edge rusher Micah Parsons briefly left Sunday's game, missing five plays while being checked in the sideline medical tent.

Ravens edge rusher David Ojabo went on injured reserve ahead of Sunday's win over the Browns and he may not be back this season.

The Saints' offense had another lackluster performance in Sunday's loss to the Buccaneers.

The Colts lost a key defensive player in Sunday's loss to the Rams.

The Packers placed left tackle David Bakhtiari on injured reserve last week and head coach Matt LaFleur didn't have anything to say about what the future holds for a veteran who has been battling knee issues for several years.

Sunday's blowout loss to the Cowboys was the final proof that Tom E. Curran needed about the true identity of this Patriots team.

The 49ers' rivalry with the Dallas Cowboys runs deep, and that was evident as Dak Prescott spoke to the media Sunday.

Lions wide receiver Jameson Williams was suspended for six games this offseason, but a revision to the NFL's gambling policy last week meant that Williams' suspension came to an end two weeks earlier than expected.

Chargers pass rusher Khalil Mack had a career-high six sacks on Sunday, but he acknowledged afterward that it wasn't all him.

Russ Francis made the Pro Bowl three times with the Patriots and won Super Bowl XIX with the Niners

49ers running back Christian McCaffrey had a terrific outing in Sunday's 35-16 victory over the Cardinals, gaining 177 yards from scrimmage and scoring four touchdowns on 27 touches.

The Patriots got blown out by the Dallas Cowboys on Sunday, Bill Belichick is asked about Mac Jones' deicsion-making after he was benched in the second half.Bill Belichick talks Mac Jones' decision-making vs. Cowboys originally appeared on NBC Sports Boston

The 49ers on Monday released an economic impact report to announce Levi's Stadium has generated more than $2 billion through 49ers games, one Super Bowl, other major sporting events and concerts.

Justin Herbert isn't expected to miss time after suffering a fractured finger and nail injury on his left hand.

Yahoo Sports' Jason Fitz and Frank Schwab discuss onZero Blitzthe Buffalo Bills' impressive win over the Miami Dolphins in Week 4, and what it means for both teams for the rest of the season. Subscribe toZero BlitzonApple,Spotify,or wherever you get your podcasts.

The Chiefs escaped MetLife Stadium with a win on Sunday night, but quarterback Patrick Mahomes certainly did not have his best performance.

The Bears have searched everywhere for answers. After blowing a 21-point lead vs. the Broncos, how they respond, if at all, will tell us what direction the rebuild and franchise are headed.

There's a new MVP favorite after Week 4 of the NFL season.

Brock Purdy came up with the perfect description of Christian McCaffrey's talents after the 49ers' win Sunday.