Article 2ZDYJ Tiny robots in a mouse's stomach help heal an ulcer

Tiny robots in a mouse's stomach help heal an ulcer

by
David Pescovitz
from on (#2ZDYJ)

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Tiny micromotors about the width of a human hair traveled through a mouse's stomach delivering antibiotics to treat a stomach ulcer. The motors are powered by bubbles. According to the researchers from the University of California San Diego, the microrobot-based treatment proved more effective than regular doses of the medicine. From New Scientist:

The tiny vehicles consist of a spherical magnesium core coated with several different layers that offer protection, treatment, and the ability to stick to stomach walls. After they are swallowed, the magnesium cores react with gastric acid to produce a stream of hydrogen bubbles that propel the motors around. This process briefly reduces acidity in the stomach. The antibiotic layer of the micromotor is sensitive to the surrounding acidity, and when this is lowered, the antibiotics are released...

The next steps are to look at a larger animal study, followed by eventual trials in humans. "There is still a long way to go, but we are on a fantastic voyage," says (researcher Joseph) Wang.

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