Week 2 Betting Preview: Predictions for every matchup
Each week during the NFL season, theScore's Dane Belbeck will handicap every matchup and offer up a three-pack of picks.

New England Patriots at New Orleans Saints (+6.5)
The New England Patriots getting blown out at home by the Kansas City Chiefs was certainly the most shocking result of Week 1, and it doesn't get easier for the defending Super Bowl champions this Sunday. A trip to the Superdome to face the New Orleans Saints awaits, and the NFC South club needs a win after a Monday loss to the Minnesota Vikings. Alex Smith picked the Patriots apart last week, and that definitely bodes well for Drew Brees. While the extended time off should help New England, it's tough to see them winning by a touchdown in New Orleans. Patriots 28, Saints 27

Philadelphia Eagles at Kansas City Chiefs (-5.5)
If the Kansas City Chiefs were able to slow Tom Brady and the Patriots last week, they should have little problem with Carson Wentz and the Eagles on Sunday afternoon. The loss of star safety Eric Berry to an Achilles injury is certainly noteworthy, but the Chiefs' offense should be able to overcome that in their home opener. That may sound weird given that Alex Smith is the quarterback, but the club showed in Week 1 that it's a new day in Kansas City for that unit. Chiefs 24, Eagles 13

Washington Redskins at Los Angeles Rams (-2.5)
The Los Angeles Rams hammered the Indianapolis Colts in Week 1, while the Washington Redskins struggled in a home loss to the Philadelphia Eagles. A west coast trip is probably the last thing Washington wants at this point, especially to face its former offensive coordinator Sean McVay, who is now the Rams' frontman. Jared Goff looked incredible against the Colts, while Kirk Cousins appeared to miss McVay's leadership greatly in Week 1. Look for that to continue on Sunday as the Rams get to 2-0 on the year. Rams 27, Redskins 20
Remaining matchupsCleveland Browns (+8) at Baltimore Ravens
This might sound weird, but a Cleveland Browns quarterback looked somewhat competent in Week 1. DeShone Kizer didn't get the win in his debut, but he definitely gave the fan base hope going forward at the position. The Baltimore Ravens feasted on the Cincinnati Bengals with four interceptions, but should struggle to move the ball against the Browns defense. Ravens 21, Browns 17
Buffalo Bills (+7.5) at Carolina Panthers
Nobody knows the Carolina Panthers better than new Buffalo Bills coach Sean McDermott. That familiarity will keep this one close and help the AFC East club cover the spread. Panthers 20, Bills 14
Arizona Cardinals at Indianapolis Colts (+7)
The Indianapolis Colts were undoubtedly the worst team in the league in Week 1, but without David Johnson, the Arizona Cardinals shouldn't be a 7-point favorite on the road over anybody. This one has the potential to be very ugly, so take the points. Cardinals 17, Colts 14
Tennessee Titans (-1.5) at Jacksonville Jaguars
Those thinking of picking the Tennessee Titans on the road in Jacksonville should probably be aware of the following stat:
Titans at -2.5 in Jacksonville on Sunday. They're a ridiculous 1-16-1 ATS in their last 18 divisional road games. pic.twitter.com/ji6UDGs7by
- Joe Osborne (@JTFOz) September 13, 2017
That being said, the Titans line isn't giving up 10 sacks like the Texans did to the Jaguars last week, so let's get crazy with this one. Titans 24, Jaguars 17
Minnesota Vikings at Pittsburgh Steelers (-5.5)
The Minnesota Vikings looked strong in a Week 1 win over the New Orleans Saints, but a stiffer test awaits with the Pittsburgh Steelers' high-powered offense. Le'Veon Bell didn't have much of an impact in his return to action, but look for him to rebound with a monster day versus Minnesota. Steelers 28, Vikings 17
Chicago Bears at Tampa Bay Buccaneers (-7)
As a result of Hurricane Irma, the Tampa Bay Buccaneers' season-opener also marks the return of former quarterback Mike Glennon. The Chicago Bears' new pivot looked decent in his debut with the club, but the Bucs know him better than anyone and will expose his weaknesses. Buccaneers 28, Bears 17
Miami Dolphins (+5.5) at Los Angeles Chargers
The Miami Dolphins were the other team affected by Hurricane Irma, meaning Sunday's game against the Los Angeles Chargers is Jay Cutler's first start for the club. That's not exactly a confidence-building situation, but the Chargers aren't running away from anybody. Chargers 27, Dolphins 24
New York Jets at Oakland Raiders (-13)
The New York Jets are starting Josh McCown in a road game on the West Coast. Not much else needs to be said here. Raiders 30, Jets 10
Dallas Cowboys (-2.5) at Denver Broncos
Ezekiel Elliott will run wild against the Denver Broncos and get the Cowboys a massive road win. Cowboys 24, Broncos 21
San Francisco 49ers at Seattle Seahawks (-14)
The Seattle Seahawks' defense looked solid against the Green Bay Packers last week, but the offense was absolutely dreadful. That showing causes some hesitation when betting a 14-point spread, but it's tough to see the 49ers scoring many points. Seahawks 20, 49ers 3
Green Bay Packers (+3) at Atlanta Falcons
The Atlanta Falcons didn't look great in barely beating the Chicago Bears, and Aaron Rodgers looks as good as ever. Packers 31, Falcons 28
Detroit Lions (+3.5) at New York Giants
Odell Beckham Jr.'s comments on Thursday didn't exactly inspire confidence that he will make his return from an ankle injury for Monday's game against the Detroit Lions. After watching the New York Giants' debacle without him in Week 1 against the Cowboys, it's a must-bet scenario to take Detroit. Lions 20, Giants 14
| Picks summary |
|---|
| Saints +6.5 (Gold) |
| Chiefs -5.5 (Silver) |
| Rams -2.5 (Bronze) |
| Browns +8 |
| Bills +7.5 |
| Colts +7 |
| Titans -1.5 |
| Steelers -5.5 |
| Buccaneers -7 |
| Dolphins +5.5 |
| Raiders -13 |
| Cowboys -2.5 |
| Seahawks -14 |
| Packers +3 |
| Lions +3.5 |
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