Coronavirus live: Parisians flee capital before midnight lockdown; Brazil records 90,570 Covid cases in 24 hours – as it happened

New restrictions begin in Paris at midnight; 2,815 Covid-19 deaths recorded in Brazil; WHO vaccine safety panel backs AstraZeneca vaccine

• Ireland resumes rollout but with advisory warning
• It's a good day': enthusiasm in Berlin as AstraZeneca jabs resume
  
• France limits AstraZeneca Covid jab to over-55s as Europe treads warily
• Brazil stares into the abyss as Covid intensive care units fill up
• Norwegian PM Erna Solberg investigated for Covid rules breach

12.11am GMT

Here's a roundup of the key moments of this evening:

Related: US reaches 100m Covid vaccine milestone six weeks early as Fauci urges vigilance - live

10.55pm GMT

Ecuador's health minister has resigned less than three weeks on the job, the Andean country's government said on Friday, as prosecutors investigate allegations of favouritism in the rollout of coronavirus vaccines.

Surgeon Rodolfo Farfan was named health minister on March 1. Reuters could not reach Farfan for comment on Friday. He has not been accused of wrongdoing, Reuters reports.