Scientists Make Further Inroads Into Reversing Ageing Process of Cells

People could eventually be able to turn the clock back on the cell-ageing process by 30 years, according to researchers who have developed a technique for reprogramming skin cells to behave as if they are much younger. From a report: Research from the Babraham Institute, a life sciences research organisation in Cambridge, could lead to the development of techniques that will stave off the diseases of old age by restoring the function of older cells and reducing their biological age. In experiments simulating a skin wound, older cells were exposed to a concoction of chemicals that "reprogrammed" them to behave more like youthful cells and removed age-related changes. This has been previously achieved, but the new work was completed in a much a shorter time frame -- 13 days compared with 50 -- and made the cells even younger. Dr Diljeet Gill, a researcher at the Babraham Institute, said: "Our understanding of ageing on a molecular level has progressed over the last decade, giving rise to techniques that allow researchers to measure age-related biological changes in human cells. We were able to apply this to our experiment to determine the extent of reprogramming our new method achieved. Our results represent a big step forward in our understanding of cell reprogramming."

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