Charles Darwin autograph manuscript could fetch £700,000 at auction

Naturalist penned document in response to request for sample of his handwriting to reprint in magazine

A rare manuscript containing a passage from Charles Darwin's On the Origin of Species is to be sold at auction in November.

The document, which is expected to fetch between 530,000 and 700,000, is said to be the most significant autograph manuscript by Darwin to have appeared at auction.