FDA turmoil deepens as top drug chief departs claiming she was fired

Dr Tracy Beth Hoeg, the Food and Drug Administration's top drug regulator, says she was fired from agency after declining to resign

In a major shake-up at the US Food and Drug Administration (FDA), top regulators left on Friday - including Tracy Beth Hoeg, the acting drug chief, who says she was fired, and Katherine Szarama, the acting vaccines chief who has only been in the position for days. Jim Traficant, the chief of staff, has also been ousted.

The FDA now has no permanent commissioner or deputy commissioner and no permanent leaders of two major centers, after the resignation of Marty Makary on Tuesday and other high-profile departures.