How to Bet on College Football Week 1 Including Clemson vs. LSU and Louisville vs. Ole Miss

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. College football Week 1 is here, and here are some of the biggest matchups this weekend. Clemson vs. LSU headlines Saturday night, while No. 24 Louisville takes on No. 9 Ole Miss on Sunday in the only matchup this week featuring two Top 25 teams. Another chapter of this battle between the Tigers takes place in Baton Rogue. All the eyes will be on Lane Kiffin and LSU as he begins his tenure with a roster transformed by the transfer portal. Dabo Swinney is looking to get the Tigers back into the ACC and national championship conversation with Christopher Vizzina taking over at quarterback, Then the attention shifts to Kiffin's former program, Ole Miss. The Rebels are led by the dynamic duo of quarterback Trinidad Chambliss and running back Kewan Lacy. The Rebels enter the season with plenty of expectations, after making a deep CFP run last season, but first they have an early-season test. Louisville is looking to prove it belongs among the ACC's best and get a major upset against one of the best in the SEC. Whether you're taking Clemson to avenge last year's 17-10 loss to LSU, riding with Kiffin and Leavitt in their first game together or looking toward Louisville vs. Ole Miss, Week 1 of college football is covered by your favorite sportsbooks like FanDuel, DraftKings, bet365 and more. FanDuel Bet $5, Get $350 in Bet Reset Tokens for 7 Days Week 1 Best Matchups *Odds may differ each site* No. 11 LSU vs. Clemson No. 24 Louisville vs. No. 9 Ole Miss No. 2 Oregon vs. Boise State DraftKings Claim the New User Offer No Promo Code Needed *Odds may differ each site* Caesars Sportsbook Sign Up and Claim the Caesars Sportsbook Promo Code *Odds may differ each site* bet365 How to claim bet365 Promo with Bonus Code FOX365'. BetMGM How to Sign Up and Claim the BetMGM Sportsbook Bonus Code