2026 NFL Odds Week 4: Lines, Spreads, Results For All 16 Games

Week 4 is here, and it kicks off with a Thursday tilt between the Steelers and Browns. Here are the lines for every Week 4 matchup at bet365 Sportsbook as of Oct. 4. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Spread: Steelers -2.5 (CLE covers)O/U: 37.5 (Over hits) Spread: Colts -4.5 (IND covers)O/U: 47.5 (Under hits) Spread: Cardinals -2.5 (NYG covers)O/U: 44.5 (Over hits) Spread: Texans -2.5 (DAL covers)O/U: 48.5 (Over hits) Spread: Packers -3 (Push)O/U: 38.5 (Under hits) Spread: Bengals -2.5 (JAX covers)O/U: 51.5 (Under hits) Spread: Rams -3.5 (LAR covers)O/U: 42.5 (Over hits) Spread: Bills -7 (NE covers)O/U: 49.5 (Over hits) Spread: Bears -3.5 (CHI covers)O/U: 43.5 (Under hits) Spread: Ravens -11.5 (TEN covers)O/U: 42.5 (Under hits) Spread: Vikings -9.5Moneyline: Vikings -575, Dolphins +425O/U: 38.5 Spread: 49ers -2.5Moneyline: 49ers -150, Broncos +125O/U: 48.5 Spread: Chiefs -4.5Moneyline: Chiefs -225, Raiders +185O/U: 47.5 Spread: Seahawks -7Moneyline: Seahawks -360, Chargers +280O/U: 42.5 Spread: Lions -3.5Moneyline: Lions -205, Panthers +170O/U: 51.5 Spread: Saints -1.5Moneyline: Saints -130, Falcons +110O/U: 48