‘This could be a real game-changer’: protein points to cure for life-limiting disease

Doctors treating boy victim of PAH raise hopes for a drug to beat a condition that leaves patients breathless, exhausted and prone to heart attacks

Archie Strachan was two when he displayed symptoms of the disease that has since blighted his life. "One night he started screaming in pain," said his mother, Julia. "Doctors flew Archie to hospital, where we eventually found he was suffering from a condition called pulmonary arterial hypertension."

The disease, known as PAH, leaves the sufferer breathless, exhausted and prone to heart failure. Twenty years ago it was considered a death sentence; even today the condition - which affects around 6,500 people in the UK - is considered debilitating and life-limiting.

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