Antibiotics: New class shows promise against plague, multi-drug resistant bacterial infections

Pathogenic bacteria are rapidly developing resistance to the arsenal of microbial therapies - and driving researchers to identify families of therapeutics with new modes of action. Recently, those include antibiotics that inhibit LpxC, an enzyme critical to forming the outer membrane of Gram-negative bacteria. This week in mBio, an international group of scientists report on laboratory ["]

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