Rare genetic mutation found in Amish community could combat ageing

Discovery of mutation which appears to protect against biological ageing raises hopes for new treatments to prevent age-related disorders

The discovery of a rare genetic mutation that prolongs human life has raised hopes for new treatments to combat ageing and prevent age-related disorders from heart disease to dementia.

Researchers spotted the mutation in an Amish population in Indiana where carriers were found to have better metabolic health, far less diabetes, and tended to live a decade longer than others in the community.