Podcast: Supercomputing New Enzymes for Breaking Down Plastics

In this TACC podcast, Gregg Beckham from NREL and Lee Woodcock from the University of South Florida describe how they are using supercomputers to engineer an enzyme that breaks down plastic. "We used computer simulations to understand how a polymeric ligand like PET would be able to bind to the enzyme," said study co-author Gregg Beckham, a Senior Research Fellow and Group Leader at the US National Renewable Energy Laboratory (NREL). "We also conducted experimental work to show that indeed, the PETase can break down water or soda bottles, industrially relevant PET films, and another plastic, polyethylene furanoate."

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