Dexamethasone may be part of the Covid-19 puzzle but it's no magic bullet | Devi Sridhar

If this cheap steroid reduces deaths in critically ill patients that's great news, and one small step towards managing coronavirus

Right now, we could all use some good news, and it came yesterday in the form of dexamethasone. This cheap steroid could significantly reduce deaths in critically ill Covid-19 patients by one-third for those on ventilators and by one-fifth for those on oxygen alone. The drug appears to stop the damage from the severe immune reaction, called a cytokine storm", that researchers increasingly believe is responsible for causing some patients to have multiple organ failure and ultimately die. Had we been able to use dexamethasone from the start of the epidemic in the UK, scientists estimate up to 5,000 lives could have been saved.

Off the back of these results, the NHS has announced that treatment protocols for Covid-19 patients will now include this drug, which is widely and easily available. This will also have a major impact in low- and middle-income countries as, unlike an expensive new patent drug that would be beyond their financial reach, dexamethasone costs just 5 per patient in the UK, and even less in other countries.