Does the key to anti-ageing lie in our bones?

Osteocalcin, a hormone produced in the bones, could one day provide treatments for age-related issues such as muscle and memory loss

Gerard Karsenty was a young scientist trying to make a name for himself in the early 1990s when he first stumbled upon a finding that would go on to transform our understanding of bone, and the role it plays in our body.

Karsenty had become interested in osteocalcin, one of the most abundant proteins in bone. He suspected that it played a crucial role in bone remodelling - the process by which our bones continuously remove and create new tissue - which enables us to grow during childhood and adolescence, and also recover from injuries.