What is the best hardware to use with LMDE 4?

My current computer is showing its age. I would like to acquire/build a better computer using the best that can be found. The problem may be that budget constraints may cause me to compromise. What I want is hardware that will be fully compatible with LMDE 4. Would prefer the best AMD processor, best motherboard with the best chipset, and best graphics card(s) for compatibility with LMDE 4. I would like to know what is the best even if it does not conform to my preferences.

IN GOD WE TRUST