Having both serial and SPI with a single FTDI4232H chip

Hello,

I have a product based on the FTDI4232H chip (having total of four ports).
Each port of this chip supports UART/SPI/I2S/GPIO.
It seems the Linux kernel automatically loads ftdi_sio driver
and makes the d2xx way of controlling the chip not working.

How can I have for example port A and B configured as ttyUSB0 and ttyUSB1
and at the same time being able to control port C and D with a custom program thru d2xx.

Thanks
Dimitar