Article 5SAJ1 TB bacterium: UAB researcher describe how the exotoxin is secreted and trafficked

TB bacterium: UAB researcher describe how the exotoxin is secreted and trafficked

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Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years. Now Niederweis and colleagues at the University of Alabama at Birmingham describe the mechanism of secretion and trafficking of that toxin, TNT, which is the major cytotoxicity factor for the pathogen that [...]

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