First patients of pioneering CAR T-cell therapy ‘cured of cancer’

Cancer-killing cells still present 10 years on, with results suggesting therapy is a cure for certain blood cancers

Two of the first human patients to be treated with a revolutionary therapy that engineers immune cells to target specific types of cancer still possess cancer-killing cells a decade later with no sign of their illness returning.

The finding suggests CAR T-cell therapy constitutes a cure" for certain blood cancers, although adapting it to treat solid tumours is proving more challenging.