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Robert Califf's appointment as the new head of the Food and Drug Administration (FDA) was confirmed today, but the process was not as straightforward as the Biden administration first thought.

Senator Joe Manchin, a Virginia Democrat, urged senators to oppose Califf's appointment earlier this week, saying he bears a great deal of responsibility" for many of the US opioid overdose deaths in the years since Califf's first stint as FDA commissioner under the Obama administration.