Article 613J4 Hepatitis A: UNC scientists discover key to virus replication, show drug effectiveness

Hepatitis A: UNC scientists discover key to virus replication, show drug effectiveness

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The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases. They also found [...]

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