US Cancer Death Rate Falls 33% Since 1991, Report Says

The rate of people dying from cancer in the United States has continuously declined over the past three decades, according to a new report from the American Cancer Society. CNN reports: The US cancer death rate has fallen 33% since 1991, which corresponds to an estimated 3.8 million deaths averted, according to the report, published Thursday in CA: A Cancer Journal for Clinicians. The rate of lives lost to cancer continued to shrink in the most recent year for which data is available, between 2019 and 2020, by 1.5%. The 33% decline in cancer mortality is "truly formidable," said Karen Knudsen, chief executive officer of the American Cancer Society. The report attributes this steady progress to improvements in cancer treatment, drops in smoking and increases in early detection. In their report, researchers from the American Cancer Society also pointed to HPV vaccinations as connected to reductions in cancer deaths. HPV, or human papillomavirus, infections can cause cervical cancer and other cancer types, and vaccination has been linked with a decrease in new cervical cancer cases. Among women in their early 20s, there was a 65% drop in cervical cancer rates from 2012 through 2019, "which totally follows the time when HPV vaccines were put into use," said Dr. William Dahut, the society's chief scientific officer. "There are other cancers that are HPV-related -- whether that's head and neck cancers or anal cancers -- so there's optimism this will have importance beyond this," he said. The lifetime probability of being diagnosed with any invasive cancer is estimated to be 40.9% for men and 39.1% for women in the US, according to the new report. The new report includes data from national programs and registries, including those at the National Cancer Institute, the US Centers for Disease Control and Prevention and the North American Association of Central Cancer Registries. Data showed that the US cancer death rate rose during most of the 20th century, largely due to an increase in lung cancer deaths related to smoking. Then, as smoking rates fell and improvements in early detection and treatments for some cancers increased, there was a decline in the cancer death rate from its peak in 1991. Since then, the pace of the decline has slowly accelerated. The new report found that the five-year relative survival rate for all cancers combined has increased from 49% for diagnoses in the mid-1970s to 68% for diagnoses during 2012-18. The cancer types that now have the highest survival rates are thyroid at 98%, prostate at 97%, testis at 95% and melanoma at 94%, according to the report. Current survival rates are lowest for cancers of the pancreas, at 12%. The report does have some bad news: new cases of breast, uterine and prostate cancer have been "of concern" and rising in the United States.

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