NFL roundup: Browns and Jets shock previously unbeaten 49ers and Eagles

• Listless San Francisco suffer first defeat of season
• Dolphins stage comeback win over Panthers

Rookie Jake Moody missed a 41-yard field goal with six seconds left, leaving San Francisco stunned 19-17 by the Cleveland Browns, who ended the 49ers' regular-season winning streak at 15 on Sunday and handed quarterback Brock Purdy his first loss as an NFL starter.

Dustin Hopkins kicked four field goals for the Browns (3-2) - the last with 1:40 left, capping a drive helped by a disputed unnecessary roughness call against San Francisco (5-1). Cleveland pulled off the league's biggest upset this season without quarterback Deshaun Watson, who missed his second straight game with a bruised shoulder.