Adult ADHD May Be Associated With an Increased Risk of Dementia, Study Finds

A new study found that adult ADHD "may take a toll on the brain and is linked to a higher likelihood of developing dementia," reports the Washington Post:A study published in JAMA Network Open reported that being diagnosed with ADHD as an adult is associated with a 2.77-fold increased risk of dementia. The study only showed an association and doesn't tell us whether ADHD is a direct cause of cognitive decline. But the results suggest that "if you do have attention-deficit disorder, you're going to have more trouble with normal brain aging," said Sandra Black, a cognitive neurologist at Sunnybrook Research Institute in Toronto who was not involved in the study. "It adds another risk factor...." Notably, of the 730 participants with adult ADHD, 13.2 percent (96 participants) were diagnosed with dementia. In contrast, of the 108,388 participants without adult ADHD, just 7 percent (7,630 participants) developed dementia. Intriguingly, adults with ADHD who were taking a psychostimulant medication such as Ritalin or Adderall did not have an increased risk of developing dementia compared with those not taking medication. Only 22.3 percent of people with ADHD had taken a psychostimulant medication at any point. The Post also notes the work of Sara Becker, a postdoctoral research associate at the University of Calgary. "In a 2023 systematic review, Becker and her colleagues identified only seven previous studies investigating the link between ADHD and neurodegenerative diseases such as dementia, most of which found that adult ADHD conferred a higher dementia risk."The research highlights the importance of seeking care - and the need for more research. Treatment with psychostimulant medications may attenuate the risk, said Stephen Levine, a professor at the University of Haifa's School of Public Health in Israel and the lead author of the study. Lifestyle changes, such as better sleep and staying socially engaged, can also lower risk for dementia.... A 2020 landmark study by the Lancet Commission highlighted 12 modifiable factors for dementia that, if addressed, could mitigate the risk of dementia by up to 40 percent. Some of these factors are hearing loss, excessive alcohol intake and smoking. Other lifestyle changes that lower your risk of demential include keeping up your physical activity, and eating a Mediterranean diet, the Post reports (citing cognitive neurologist Sandra Black). An estimated 3 percent of adults have ADHD.

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