First Thing: Biden to issue order on new restrictions at US-Mexico border

President's move comes amid voter dissatisfaction over migration, while progressive and Latino lawmakers express alarm. Plus, world's first personalized cancer vaccine halves the risk of death from melanoma

Good morning.

Joe Biden is expected to announce an executive order on Tuesday that would instruct authorities to temporarily seal the border with Mexico when illegal crossings exceed a daily threshold, in the harshest border action taken so far by his administration.

What's been the reaction? Many progressive and Hispanic lawmakers were alarmed at the comprehensive order, and legal challenges are expected.

How does it work? The jab, which is personalized for each patient, instructs their body to kill any remaining cancer cells and stop the disease from returning.