2025 NFL schedule release, odds, betting: Cowboys-Eagles headlines full list of Week 1 spreads

The 2025 NFL schedule has been released, and we now know the full schedules for all 32 NFL teams, including Sunday Night Football, Monday Night Football, international games, Thursday Night Football, and Thanksgiving and Christmas games.

It also means we're inching closer to the season and finally can turn our attention to actual numbers for the games, including spreads for Week 1, which have been released at BetMGM.

Here are the odds for all 16 Week 1 games for the 2025 season:

Thursday, Sept. 4

Dallas Cowboys at Philadelphia Eagles (-7, 46.5)

Friday, Sept. 5

Kansas City Chiefs (-2.5, 44.5) vs. Los Angeles Chargers (in Sao Paulo)

Sunday, Sept. 7

1 p.m. ET games

Arizona Cardinals (-4.5, 41.5) at New Orleans Saints

Cincinnati Bengals (-5.5, 45.5) at Cleveland Browns

Miami Dolphins at Indianapolis Colts (-1.5, 45.5)

Las Vegas Raiders at New England Patriots (-2.5, 43.5)

New York Giants at Washington Commanders (-7, 45.5)

Tampa Bay Buccaneers (-1.5, 48.5) at Atlanta Falcons

Carolina Panthers at Jacksonville Jaguars (-3, 46.5)

Pittsburgh Steelers (-3, 39.5) at New York Jets

4 p.m. ET games

Houston Texans at Los Angeles Rams (-2.5, 46.5)

San Francisco 49ers (-1.5, 45.5) at Seattle Seahawks

Tennessee Titans at Denver Broncos (-7, 41.5)

Detroit Lions (-1.5, 49.5) at Green Bay Packers

Sunday Night Football

Baltimore Ravens at Buffalo Bills (-1.5, 51.5)

Monday, Sept. 8

Minnesota Vikings (-1.5, 44.5) at Chicago Bears