First Thing: Israel attacks Iran’s Arak heavy-water reactor as Iran hits Israeli hospital

Israeli defence minister acknowledges goal of war is to attack symbols of the regime'. Plus, only two years left to meet 1.5C warming target

Good morning.

Israel's defence minister has said he ordered increased attacks on government targets in Iran to undermine the regime", while an Iranian missile evaded Israeli air defences to hit a hospital in the country's south.

How is Israel's military strategy shifting? When Israel launched its first strikes, Benjamin Netanyahu said he had ordered a strategic operation targeting Iran's nuclear programme, although the Israeli prime minister has made no secret of his hopes that the government in Tehran would fall. After the initial focus on military and nuclear sites, Israel recently attacked targets with no links to the nuclear project, but which Katz described as symbols of the regime", including the state broadcaster.

What is the latest on the conflict? Israel attacked Iran's Arak heavy-water reactor early on Thursday, Iranian state television reported. In Israel, Soroka hospital in Beersheba was hit by a ballistic missile, Israeli officials said, after Iran launched its latest wave of retaliatory airstrikes. Read our live blog here.