Daily weight loss pill can help cut body weight by a fifth, trial shows

One in five people who took orforglipron once a day for 72 weeks lost 20% or more of their weight, maker Eli Lilly says

A daily pill for weight loss can help people reduce their body weight by as much as a fifth, according to a trial that could pave the way for millions more people to shed pounds.

The drug, called orforglipron, is manufactured by Eli Lilly and targets the same GLP-1 receptors as weight loss injections such as Mounjaro and Wegovy. In a trial of 3,127 adults, one in five people who took the once-a-day tablet for 72 weeks lost 20% or more of their body weight.