2026 NFL No. 1 Seed Odds: Bills Overtake Chiefs In AFC; 49ers Atop NFC

Earning the No. 1 seed gives a team a first-round bye and home-field advantage throughout the conference playoffs - two major advantages in the chase for the Lombardi. Since 2013, six of the 13 Super Bowl winners have been the top seed in their respective conference. Through seven weeks, the Bills and 49ers lead the oddsboard. Let's check out the No. 1 seed odds for both the AFC and NFC at DraftKings Sportsbook as of Oct. 29. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. No. 1 Seed Odds AFC Buffalo Bills: +210Kansas City Chiefs: +250Jacksonville Jaguars: +700Denver Broncos: +700Cincinnati Bengals: +700New England Patriots: +1100Baltimore Ravens: +1500Pittsburgh Steelers: +3000Cleveland Browns: +7400Las Vegas Raiders: +25000Houston Texans: +25000New York Jets: +50000Indianapolis Colts: +70000Tennessee Titans: +100000Miami Dolphins: +100000Los Angeles Chargers: not listed What to know: Last season, the Broncos earned the AFC's No. 1 seed before falling to the Patriots in heartbreaking fashion in the AFC Championship Game. In 2023, the Ravens finished 13-4 to secure the top seed but were eliminated by Kansas City in the conference championship. The Bills are back atop the oddsboard. Buffalo is now favored at +210 to earn the AFC's No. 1 seed, overtaking the Chiefs after Kansas City's blowout loss to the Seahawks last week. The Bills are chasing their first top seed since 1993. The Chiefs, meanwhile, have slipped to +250 after Seattle held them to just three points. Sunday's loss was the first time in Patrick Mahomes' career that the Chiefs did not take a snap from the red zone. But despite the loss, K.C. is still 5-1 and in first place in the AFC West. Kansas City has claimed the top seed four times with Patrick Mahomes as its starter (2018, 2020, 2022 and 2024), reaching the Super Bowl in each of the last three instances. NFC San Francisco 49ers: +115Minnesota Vikings: +250Detroit Lions: +750Chicago Bears: +850Seattle Seahawks: +950Los Angeles Rams: +3500Green Bay Packers: +4000Carolina Panthers: +6000New York Giants: +7400Dallas Cowboys: +9000Atlanta Falcons: +10000Washington Commanders: +30000Tampa Bay Buccaneers: +50000Philadelphia Eagles: +50000New Orleans Saints: +50000Arizona Cardinals: +50000 What to know: The Seahawks earned the NFC's No. 1 seed in 2025, with home-field advantage helping Seattle on its way to a Lombardi Trophy. The Rams finished with the conference's second-best record but were the No. 5 seed after finishing second in the NFC West. In 2024, the Lions went 15-2 to claim the top seed before being upset at home in the divisional round. The Eagles and 49ers earned the No. 1 seed in 2022 and 2023, respectively, and both reached the Super Bowl before losing to the Chiefs. San Francisco still leads the oddsboard, but the race is tightening. After a 6-0 start that included wins over the Rams, Broncos and Seahawks, the 49ers dropped their first game of the season to the Falcons last week. Their odds to earn the NFC's No. 1 seed have since moved from -140 to +115, giving the rest of the conference an opening. San Francisco has been the No. 1 seed twice under Kyle Shanahan, in 2019 and 2023, and reached the Super Bowl both times. But its NFC West rivals are closing the gap after big wins of their own. The Seahawks jumped from +2000 to +950 after dominating the Chiefs. Meanwhile, the Rams improved from +4000 to +3500 after a much-needed victory in which Matthew Stafford became the franchise's all-time passing touchdown leader. The NFC West race should be a wild ride through early January.