NFL Week 10 betting: 5 biggest storylines, including how the Jaguars' trades affected Super Bowl odds

Favorites ruled the NFL in Week 9.

Favorites were 14-1 straight up and 11-3-1 against the spread. The week started with the Jacksonville Jaguars easily winning and covering as a 10-point favorite at the Baltimore Ravens last Thursday night, and it ended with the Buffalo Bills easily winning and covering as a 3-point favorite at the offensively inept Minnesota Vikings on Monday night. It was such a chalky week that only one of 610 remaining entries in Circa Sports' survivor contest was eliminated, according to Yahoo Sports' Ben Fawkes, with a pick on the Falcons.

Here are the top five betting storylines as we head into Week 10 of the NFL season:

Jaguars make a splash

The Jaguars made three trades on Monday, first for safety Jessie Bates III from the Falcons, then for defensive tackle Davon Godchaux from the Saints and a big move for defensive tackle Jordan Davis from the Eagles.

Oddsmakers took note. The Jaguars, already 6-2 and atop the NFL in DVOA and point differential, moved to third in the Super Bowl odds at +750 at BetMGM. They trail only the 49ers and Bills, who are tied for the top spot at +550

The Jaguars' first test after the trade deadline shouldn't be too tough: They're a 10.5-point road favorite against the Titans in Week 10.

Trevor Lawrence and the Jacksonville Jaguars are among the Super Bowl favorites.Cooper Neill via Getty ImagesA new MVP favorite

With another big game, Joe Burrow has pushed ahead of Josh Allen for the top spot in the MVP odds. Burrow is +200 and Allen is right behind at +225 at BetMGM. Burrow has been on a hot streak and has a favorable schedule in November that gave him a shot at becoming the clear favorite to win the award.

At roughly the midpoint of the season, oddsmakers have the race down to five players: Burrow, Allen, Brock Purdy (+450), Jordan Love (+700) and Trevor Lawrence (+750). Everyone else is 30-to-1 odds or longer at BetMGM. Caleb Williams slipped to 30-to-1 after his four-interception game in Week 9.

Chargers still winless ATS

The Los Angeles Chargers are making a run at history.

The Chargers are 0-7-1 against the spread (or 0-8, depending on the line for a 7-point loss to the Seahawks in Week 4), the only team in the NFL that hasn't had a win for bettors. Every other team in the NFL has covered the spread at least twice, except the Eagles who are 1-8 ATS.

The Chargers are stunningly bad this season and are 5-point underdogs in Week 10 to a Ravens team that will be on its fourth starting quarterback of the season, Jacoby Brissett. At some point the Chargers will cover a spread, but bettors are still waiting for it.

Giants favored on Thursday, and to win NFC East

The New York Giants face a big divisional game on Thursday that can strengthen what is already a tight grip on first place in the NFC East.

The Giants play the Washington Commanders on Thursday night, and they're favored by 2.5 points at home. With the win, they'd be four games up on the Commanders and own the head-to-head tiebreaker. That would leave the Giants and Cowboys as the only two contenders in the division. The Giants are a heavy -220 favorite to win the NFC East and those odds would get even shorter if they win as a favorite to kick off Week 10.

Rams now favored to miss playoffs

The Los Angeles Rams won on Sunday but lost receiver Puka Nacua to a knee injury that will keep him out for a while. That injury, and the depth of the NFC's wild-card race, have made it more likely than not that the Rams miss the playoffs according to oddsmakers.

The "no" for the Rams making the playoffs is at -118 odds at BetMGM. "Yes" is -102. The preseason Super Bowl favorite is in real danger of missing the postseason altogether.