Article V0A5 Biohackers push life to the limits with DIY biology

Biohackers push life to the limits with DIY biology

by
Kim Wall
from on (#V0A5)

For the next generation of hackers, micro organisms have become the new hardware and DNA strands the new software

The petri dish spells it out in faint, dark letters: "Ceci n'est pas un E coli." The play on the classic painting has a twist, though: while Magritte insisted his caption was accurate since it wasn't a pipe but an image of one, here, the canvas really is Escherichia coli. Or at least it was, before it was genetically modified for capabilities far beyond its own.

Since E coli's natural habitat - the darkness of the human intestine - doesn't warrant light sensitivity, a sensor is added. Another upgrade instructs the bacteria to excrete an enzyme to stain the dish's agar solution black when hit by light. The image itself is captured through a negative putting only the lit-up bacteria to work - the brighter the light, the darker the spot - and voili: about a day later, a bacterial photograph.

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