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Updated 2025-09-09 04:17
This baby boy was treated with the first personalized gene-editing drug
Doctors say they constructed a bespoke gene-editing treatment in less than seven months and used it to treat a baby with a deadly metabolic condition. The rapid-fire attempt to rewrite the child's DNA marks the first time gene editing has been tailored to treat a single individual, according to a report published in the New...
The Download: Montana’s experimental treatments, and Google DeepMind’s new AI agent
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. The first US hub for experimental medical treatments is coming The news: A bill that allows clinics to sell unproven treatments has been passed in Montana. Under the legislation, doctors can apply for...
How US research cuts are threatening crucial climate data
Over the last few months, and especially the last few weeks, there's been an explosion of news about proposed budget cuts to science in the US. One trend I've noticed: Researchers and civil servants are sounding the alarm that those cuts mean we might lose key data that helps us understand our world and how...
Google DeepMind’s new AI agent cracks real-world problems better than humans can
Google DeepMind has once again used large language models to discover new solutions to long-standing problems in math and computer science. This time the firm has shown that its approach can not only tackle unsolved theoretical puzzles, but improve a range of important real-world processes as well. Google DeepMind's new tool, called AlphaEvolve, uses the...
The first US hub for experimental medical treatments is coming
A bill that allows medical clinics to sell unproven treatments has been passed in Montana. Under the legislation, doctors can apply for a license to open an experimental treatment clinic and recommend and sell therapies not approved by the Food and Drug Administration (FDA) to their patients. Once it's signed by the governor, the law...
The Download: taking the temperature of snow, and the future of privacy
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. Why climate researchers are taking the temperature of mountain snow The Sierra's frozen reservoir provides about a third of California's water and most of what comes out of the faucets, shower heads, and...
Why climate researchers are taking the temperature of mountain snow
On a crisp morning in early April, Dan McEvoy and Bjoern Bingham cut clean lines down a wide run at the Heavenly Ski Resort in South Lake Tahoe, then ducked under a rope line cordoning off a patch of untouched snow. They side-stepped up a small incline, poled past a row of Jeffrey pines, then...
The Download: CRISPR in court, and the police’s ban-skirting AI
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. A US court just put ownership of CRISPR back in play The CRISPR patents are back in play. Yesterday, the US Court of Appeals for the Federal Circuit said scientists Jennifer Doudna and...
Police tech can sidestep facial recognition bans now
Six months ago I attended the largest gathering of chiefs of police in the US to see how they're using AI. I found some big developments, like officers getting AI to write their police reports. Today, I published a new story that shows just how far AI for police has developed since then. It's about...
A US court just put ownership of CRISPR back in play
The CRISPR patents are back in play. On Monday, the US Court of Appeals for the Federal Circuit said scientists Jennifer Doudna and Emmanuelle Charpentier will get another chance to show they ought to own the key patents on what many consider the defining biotechnology invention of the 21st century. The pair shared a 2020...
The Download: a new form of AI surveillance, and the US and China’s tariff deal
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. How a new type of AI is helping police skirt facial recognition bans Police and federal agencies have found a controversial new way to skirt the growing patchwork of laws that curb how...
How a new type of AI is helping police skirt facial recognition bans
Police and federal agencies have found a controversial new way to skirt the growing patchwork of laws that curb how they use facial recognition: an AI model that can track people using attributes like body size, gender, hair color and style, clothing, and accessories. The tool, called Track and built by the video analytics company...
How cloud and AI transform and improve customer experiences
As AI technologies become increasingly mainstream, there's mounting competitive pressure to transform traditional infrastructures and technology stacks. Traditional brick-and-mortar companies are finding cloud and data to be the foundational keys to unlocking their paths to digital transformation, and to competing in modern, AI-forward industry landscapes. In this exclusive webcast, experts discuss the building blocks for...
The Download: AI headphone translation, and the link between microbes and our behavior
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. A new AI translation system for headphones clones multiple voices simultaneously What's new: Imagine going for dinner with a group of friends who switch in and out of different languages you don't speak,...
Your gut microbes might encourage criminal behavior
A few years ago, a Belgian man in his 30s drove into a lamppost. Twice. Local authorities found that his blood alcohol level was four times the legal limit. Over the space of a few years, the man was apprehended for drunk driving three times. And on all three occasions, he insisted he hadn't been...
A new AI translation system for headphones clones multiple voices simultaneously
Imagine going for dinner with a group of friends who switch in and out of different languages you don't speak, but still being able to understand what they're saying. This scenario is the inspiration for a new AI headphone system that translates the speech of multiple speakers simultaneously, in real time. The system, called Spatial...
The Download: AI benchmarks, and Spain’s grid blackout
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. How to build a better AI benchmark It's not easy being one of Silicon Valley's favorite benchmarks. SWE-Bench (pronounced swee bench") launched in November 2024 as a way to evaluate an AI model's...
Roundtables: A New Look at AI’s Energy Use
Wednesday, May 21, 2025 Big Tech's appetite for energy is growing rapidly as adoption of AI accelerates. But just how much energy does even a single AI query use? And what does it mean for the climate? Join editor in chief Mat Honan, senior climate reporter Casey Crownhart, and AI reporter James O'Donnell for a...
The business of the future is adaptive
Manufacturing is in a state of flux. From supply chain disruptions to rising costs, tougher environmental regulations, and a changing consumer market, the sector faces a series of competing challenges. But a new way of operating offers a way to tackle complexities head-on: adaptive production hardwires flexibility and resilience into the enterprise, drawing on powerful...
The Download: Neuralink’s AI boost, and Trump’s tariffs
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. This patient's Neuralink brain implant gets a boost from generative AI Last November, Bradford G. Smith got a brain implant from Elon Musk's company Neuralink. The device, a set of thin wires attached...
This patient’s Neuralink brain implant gets a boost from generative AI
Last November, Bradford G. Smith got a brain implant from Elon Musk's company Neuralink. The device, a set of thin wires attached to a computer about the thickness of a few quarters that sits in his skull, lets him use his thoughts to move a computer pointer on a screen. And by last week he...
The Download: a longevity influencer’s new religion, and humanoid robots’ shortcomings
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. Bryan Johnson wants to start a new religion in which the body is God" Bryan Johnson is on a mission to not die. The 47-year-old multimillionaire has already applied his slogan Don't Die"...
Why the humanoid workforce is running late
On Thursday I watched Daniela Rus, one of the world's top experts on AI-powered robots, address a packed room at a Boston robotics expo. Rus spent a portion of her talk busting the notion that giant fleets of humanoids are already making themselves useful in manufacturing and warehouses around the world. That might come as...
Bryan Johnson wants to start a new religion in which “the body is God”
Bryan Johnson is on a mission to not die. The 47-year-old multimillionaire has already applied his slogan Don't Die" to events, merchandise, and a Netflix documentary. Now he's founding a Don't Die religion. Johnson, who famously spends millions of dollars on scans, tests, supplements, and a lifestyle routine designed to slow or reverse the aging...
The Download: foreign disinformation intel, and gene-edited pork
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. A senior State Department official demanded records of communications with journalists, European officials, and Trump critics A previously unreported document distributed by senior US State Department official Darren Beattie reveals a sweeping effort...
The US has approved CRISPR pigs for food
Most pigs in the US are confined to factory farms where they can be afflicted by a nasty respiratory virus that kills piglets. The illness is called porcine reproductive and respiratory syndrome, or PRRS. A few years ago, a British company called Genus set out to design pigs immune to this germ using CRISPR gene...
Senior State Department official sought internal communications with journalists, European officials, and Trump critics
A previously unreported document distributed by senior US State Department official Darren Beattie reveals a sweeping effort to uncover all communications between the staff of a small government office focused on online disinformation and a lengthy list of public and private figures-many of whom are longtime targets of the political right. The document, originally shared...
The Download: China’s energy throwback, and choosing between love and immortality
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. A long-abandoned US nuclear technology is making a comeback in China China has once again beat everyone else to a clean energy milestone-its new nuclear reactor is reportedly one of the first to...
A long-abandoned US nuclear technology is making a comeback in China
China has once again beat everyone else to a clean energy milestone-its new nuclear reactor is reportedly one of the first to use thorium instead of uranium as a fuel and the first of its kind that can be refueled while it's running. It's an interesting (if decidedly experimental) development out of a country that's...
The Download: stereotypes in AI models, and the new age of coding
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. This data set helps researchers spot harmful stereotypes in LLMs What's new? AI models are riddled with culturally specific biases. A new data set, called SHADES, is designed to help developers combat the...
This data set helps researchers spot harmful stereotypes in LLMs
AI models are riddled with culturally specific biases. A new data set, called SHADES, is designed to help developers combat the problem by spotting harmful stereotypes and other kinds of discrimination that emerge in AI chatbot responses across a wide range of languages. Margaret Mitchell, chief ethics scientist at AI startup Hugging Face, led the...
The Download: the AI Hype Index, and “normal” AI
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. The AI Hype Index: AI agent cyberattacks, racing robots, and musical models Separating AI reality from hyped-up fiction isn't always easy. That's why we've created the AI Hype Index-a simple, at-a-glance summary of...
The AI Hype Index: AI agent cyberattacks, racing robots, and musical models
Separating AI reality from hyped-up fiction isn't always easy. That's why we've created the AI Hype Index-a simple, at-a-glance summary of everything you need to know about the state of the industry. AI agents are the AI industry's hypiest new product-intelligent assistants capable of completing tasks without human supervision. But while they can be theoretically...
We need to start thinking of AI as “normal”
Right now, despite its ubiquity, AI is seen as anything but a normal technology. There is talk of AI systems that will soon merit the term superintelligence," and the former CEO of Google recently suggested we control AI models the way we control uranium and other nuclear weapons materials. Anthropic is dedicating time and money...
The Download: China’s manufacturers’ viral moment, and how AI is changing creativity
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. Why Chinese manufacturers are going viral on TikTok Since the video was posted earlier this month, millions of TikTok users have watched as a young Chinese man in a blue T-shirt sits beside...
Why Chinese manufacturers are going viral on TikTok
Since the video was posted earlier this month, millions of TikTok users have watched as a young Chinese man in a blue T-shirt sits beside a traditional tea set and speaks directly to the camera in accented English: Let's expose luxury's biggest secret." He stands and lifts what looks like an Hermes Birkin bag, one...
The Download: how Trump’s tariffs will affect US manufacturing, and AI architecture
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. Sweeping tariffs could threaten the US manufacturing rebound Despite the geopolitical chaos and market collapses triggered by President Trump's announcement of broad tariffs on international goods, some supporters still hope the strategy will...
Sweeping tariffs could threaten the US manufacturing rebound
Despite the geopolitical chaos and market collapses triggered by President Trump's announcement of broad tariffs on international goods, some supporters still hope the strategy will produce a golden age" of American industry. Trump himself insists, Jobs and factories will come roaring back into our country." While it's possible that very targeted tariffs could help protect...
Driving business value by optimizing the cloud
Organizations are deepening their cloud investments at an unprecedented pace, recognizing its fundamental role in driving business agility and innovation. Synergy Research Group reports that companies spent $84 billion worldwide on cloud infrastructure services in the third quarter of 2024, a 23% rise over the third quarter of 2023 and the fourth consecutive quarter in...
The Download: Apple’s eucalyptus carbon bet, and climate tech’s bad vibes
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. Inside the controversial tree farms powering Apple's carbon neutral goal We were losing the light, and still about 20 kilometers from the main road, when the car shuddered and died at the edge...
The vibes are shifting for US climate tech
The past few years have been an almost nonstop parade of good news for climate tech in the US. Headlines about billion-dollar grants from the government, massive private funding rounds, and labs churning out advance after advance have been routine. Now, though, things are starting to shift. About $8 billion worth of US climate tech...
Inside the controversial tree farms powering Apple’s carbon neutral goal
We were losing the light, and still about 20 kilometers from the main road, when the car shuddered and died at the edge of a strange forest. The grove grew as if indifferent to certain unspoken rules of botany. There was no understory, no foreground or background, only the trees themselves, which grew as a...
Roundtables: Brain-Computer Interfaces: From Promise to Product
Recorded onApril 23, 2025 Brain-Computer Interfaces: From Promise to Product Speakers: David Rotman, editor at large, and Antonio Regalado, senior editor for biomedicine. Brain-computer interfaces (BCIs) have been crowned the 11th Breakthrough Technology of 2025 byMIT Technology Reviews readers. BCIs are electrodes implanted into the brain to send neural commands to computers, primarily to assist...
The Download: introducing the Creativity issue
This is today's edition ofThe Download,our weekday newsletter that provides a daily dose of what's going on in the world of technology. Introducing: the Creativity issue The university computer lab may seem like an unlikely center for creativity. We tend to think of creativity as happening more in the artist's studio or writers' workshop. But...
3 Things Caiwei Chen is into right now
A new play about OpenAI I recently saw Doomers, a new play by Matthew Gasda about the aborted 2023 coup at OpenAI, here represented by a fictional company called MindMesh. The action is set almost entirely in a meeting room; the first act follows executives immediately after the firing of company CEO Seth (a stand-in...
Why we still need AM radio
Ariel Aberg-Riger is the author of America Redux: Visual Stories from Our Dynamic History.
Seeing AI as a collaborator, not a creator
The reason you are reading this letter from me today is that I was bored 30 years ago. I was bored and curious about the world and so I wound up spending a lot of time in the university computer lab, screwing around on Usenet and the early World Wide Web, looking for interesting things...
Unleashing the potential of qubits, one molecule at a time
It all began with a simple origami model. As an undergrad at Harvard, Danna Freedman went to a professor's office hours for her general chemistry class and came across an elegant paper model that depicted the fullerene molecule. The intricately folded representation of chemical bonds and atomic arrangements sparked her interest, igniting a profound curiosity...
The Institute’s greatest ambassadors
After decades of working as a biologist at a Southern school with a Division1 football team, coming to MIT was a bit of a culture shock-in the best possible way. I've heard from MIT alumni all about late-night psetting, when to catch MITHenge, and the best way to celebrate Pi Day (with pie, of course)....
Bug-size robots that fly and flip could pollinate futuristic farms’ crops
Tiny flying robots could perform such useful tasks as pollinating crops inside multilevel warehouses, boosting yields while mitigating some of agriculture's harmful impacts on the environment. The latest robo-bug from an MIT lab, inspired by the anatomy of the bee, comes closer to matching nature's performance than ever before. Led by Kevin Chen, an associate...
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