Up to 600 children in the first year and 2,000 the year after will be among first in Europe to receive Palforzia treatmentChildren in the UK will be the first in Europe to receive a life-changing treatment for peanut allergies, after NHS England secured a deal for a drug that decreases the severity of symptoms including anaphylaxis.The oral treatment, Palforzia, will be available to up to 600 children aged four to 17 the first year and 2,000 the following year. Continue reading...

Latest updates: researchers at Imperial College London stress that reduction in severity must be balanced with larger risk of infection

Hundreds of Roman and medieval coins and artefacts uncovered near ancient city of CaesareaArchaeologists in Israel have discovered the remnants of two shipwrecks off the Mediterranean coast, replete with a sunken trove of hundreds Roman and medieval silver coins.The finds made near the ancient city of Caesarea were dated to the Roman and Mamluk periods, about 1,700 and 600 years ago, archaeologists said. They include hundreds of Roman silver and bronze coins dating to the mid-third century, as well as more than 500 silver coins from the middle ages found amid the sediment. Continue reading...

Two weaker doses of Pfizer jab to be given, with some scientists calling for all in age group to be vaccinated• Covid vaccination for UK children: what has been approved?• Coronavirus – latest updatesHundreds of thousands of clinically vulnerable five- to 11-year-olds are to be offered Covid vaccines for the first time, with some scientists calling for the programme to be extended to the whole age group before the new UK school term.The Joint Committee on Vaccination and Immunisation (JCVI) has recommended vaccinations for about 330,000 younger children at clinical risk, and also those living with someone who is immunosuppressed. Continue reading...

Dr Tedros Adhanom Ghebreyesus says there will be enough vaccines for world’s adults – if they are not hoarded

DNA analysis of bodies in Hazleton North long cairn finds five generations of an extended familyAn analysis of DNA from a 5,700-year-old tomb has revealed the world’s oldest family tree, shedding “extraordinary” light on the importance of family and descent among people who were some of Britain’s first farmers.A research team has examined the bones and teeth of 35 people in one of Britain’s best preserved neolithic tombs, near the village of Hazleton in the Cotswolds. The results, said Dr Chris Fowler of Newcastle University, are nothing short of “astounding”. Continue reading...

Young children most vulnerable to Covid will be offered vaccine, and there are changes to booster schedules for some older onesThe UK government’s vaccine advisers have issued new guidance on Covid vaccinations for young people in light of the rapidly spreading Omicron variant. The advice opens up Covid vaccinations for children as young as five and extends the booster programme to more teenagers. Continue reading...

Industry body urges rethink on leaving out sector from aid package, saying many firms ‘will go to the wall’

Booster will also be available to medical teams and immunodeficient people four months after third dose

Scientists warn, however, that lower severity of cases is not fully understood and may not occur elsewhere

The year has been marked by the success of the vaccination drive – yet thousands have still diedThis time last year, Covid-19 cases were soaring in the UK, hospitalisations were steadily increasing, and the government had tightened restrictions to try to get a handle on a concerning new variant.Twelve months on, there is a sense of deja vu. A weary public is worried about its festive plans being cancelled, an outcome that would be all the more painful in light of the Christmas party scandal that has enveloped Downing Street in recent weeks. Continue reading...

Nicolae Ceaușescu’s Romanian communist regime hailed his wife as an eminent chemistry researcher, though she had no genuine qualifications. But her name lives on in academic journals, and British institutions have yet to retract honours bestowed on herRomanian researchers have called on academic publishers to remove Elena Ceaușescu’s name from almost two dozen scientific papers and books fraudulently published as her work, more than 30 years after the wife of the former communist dictator Nicolae Ceaușescu was executed.Elena Ceaușescu was celebrated by state propaganda under her husband’s regime as a world-famous chemistry researcher, despite having no credible qualifications. The researchers say some of her work is still being cited and accessed, even though she was barely literate in science and unable to recognise basic formulas taught to first-year chemistry students. Continue reading...

Sandy Douglas, from Oxford University, says updated vaccine could ‘respond to any new variant more rapidly’

The James Webb space telescope, considered the Hubble’s successor, will stay on the ground an extra day due to high windsDangerously high winds will keep Nasa’s newest space telescope on the ground for at least an extra day, with the launch now targeted for Saturday – Christmas Day – at the earliest.Nasa announced the latest delay Tuesday. Upper-level high wind could force a rocket off-course or even damage or destroy it. Continue reading...

President pushes back against resistance to vaccine mandates, saying they are ‘not to control your life, but to save your life’

At least 66m-year-old fossil discovered in southern China reveals posture previously unseen in dinosaursScientists have announced the discovery of an exquisitely preserved dinosaur embryo from at least 66m years ago that was preparing to hatch from its egg just like a chicken.The fossil was discovered in Ganzhou, southern China and belonged to a toothless theropod dinosaur, or oviraptorosaur, which the researchers dubbed “Baby Yingliang”. Continue reading...

Agency will give go-ahead for Pfizer and Merck to launch groundbreaking oral treatments perhaps this weekUS federal regulators are expected to approve the first pills to treat Covid-19 as early as this week, it was reported on Tuesday.According to sources quoted by Bloomberg News, the Food and Drug Administration (FDA) will give the go-ahead for Pfizer and Merck to launch groundbreaking oral treatments perhaps as soon as Wednesday. Continue reading...

Understanding service workers’ current challenges, and adjusting your expectations accordingly, can ease shopping frustrationsAs we approach our second Christmas at the mercy of a virus that just won’t quit, one would think people would have accepted that supply chain issues and other Covid-related problems might mean low stock and delayed deliveries, as has been the case for going on two years. But after speaking to business owners and frontline retail staff, it seems this is far from true.The retail workers told me that most customers were perfectly gracious and well-behaved, but all reported a small group of shoppers that were hostile – even aggressive – in-store, online and on the phone, over matters that were quite clearly out of the service worker’s control. The word traumatised came up more than once. Continue reading...

Court papers reveal how long watchdog knew of potential problems at Wolverhampton site

Paxlovid is expected to work well against Omicron. The real problem is that production is insufficientWhat if there was a pill you could take as soon as you test positive for Covid, that stopped the virus in its tracks? A pill that reduced the viral number of copies in your upper airway (known as viral load) by more than tenfold, markedly reducing contagiousness to others? And that reduced the chance of hospitalization by nearly 90%?There is such a pill, called Paxlovid, which was developed specifically for the Sars-CoV-2 virus, derived from a molecule that was effective in the lab against the original SARS virus, and is a potent inhibitor of the main protease of the virus, called Mpro. It’s the chokepoint for preventing the virus from replicating. It has been tested in two randomized clinical trials compared with a placebo, and not only was its potency established, but it proved to be as safe as the placebo.Eric Topol is the founder and director of the Scripps Research Translational Institute, professor of molecular medicine, and executive vice-president of Scripps Research Continue reading...

Largest ever specimen, a 2.7 metre-long creature known as Arthropleura, discovered by ‘fluke’ on UK beachGiant millipedes as long as a car and weighing 50kg once hunted across northern England, experts have revealed, following the discovery of a 326m-year-old fossil.The largest fossil of a giant millipede was found by a “fluke” on a Northumberland beach at Howick, after a section of cliff fell on to the shore. Continue reading...

Home-brewed yoghurt on International Space Station may be just a small leap for a group of budding scientists

Having long Covid made me reassess my health and wellbeing, and the benefits have been profoundAt the start of 2021, I was diagnosed with long Covid. It was a huge relief to finally know why I had been struggling so much with my health – extreme fatigue, continuous coughing and, most distressing of all, brain fog and panic attacks. The diagnosis was also the beginning of a journey that would take me – of all places – to a life-changing decision about what I eat.After further tests, I was told it was very likely that I had caught Covid a while ago, possibly at the start of the pandemic, before tests were available. I’m very fortunate to have a brilliant and caring GP who listens to me and provides me with support. He signed me off work for two months and helped me understand that I needed real rest to assist my recovery. Continue reading...

Reaction comes after Boris Johnson announces there will be no additional measures put in place for now

Tedros Adhanom Ghebreyesus says Omicron is infecting people who have been vaccinated and could double its infections every 1.5 to three days

Trump once again claimed credit for producing the vaccine, saying vaccine wariness was ‘playing into the hands’ of his opponentsDonald Trump revealed he received a booster shot of the Covid-19 vaccine, drawing boos from a crowd of his supporters in Dallas.The former president made the disclosure on Sunday night during the final stop of The History Tour, a live interview show he has been doing with the former Fox News host Bill O’Reilly. Continue reading...

Government mulls new measures to curb Omicron amid second highest daily case toll of pandemic, as hospitalisations in London rise ‘quite steeply’

From questionable Covid treatments to life-saving inventions and discoveries about the natural world – medical editor Melissa Davey and science writer Donna Lu talk to Laura Murphy-Oates about the best and worst science stories of 2021You can also read: Continue reading...

Loneliness is significant mental health concern and can raise risk of death by 45%, say scientistsContact with nature in cities significantly reduces feelings of loneliness, according to a team of scientists.Loneliness is a major public health concern, their research shows, and can raise a person’s risk of death by 45% – more than air pollution, obesity or alcohol abuse. Continue reading...

York-based company makes synthetic antibodies for pharmaceutical firms including AstraZenecaA British biotechnology firm that supplies big pharmaceutical firms with synthetic antibodies for targeted delivery of drugs will float in London this week valued at £80.7m – giving its two founders a combined paper fortune of more than £33m.Aptamer Group was founded in 2008 by Dr Arron Tolley, 44, an early school leaver who later completed a doctorate in biophysics and molecular biology, and Dr David Bunka, a geneticist. Today, the York-based company has partnerships with the vast majority of the world’s top 20 pharmaceutical firms, including Britain’s biggest drugmaker, AstraZeneca, and Japan’s Takeda. Continue reading...

The pandemic has given us new kinds of exhaustion, all of them equally draining. Yet there’s hope in perseveranceDuring the past two years, each stage of the pandemic has brought with it a new species of tired. The first was a heady sort of tiredness, all jittery over-vigilance when the first lockdown happened. The memory of that time has an almost lunar quality: it felt like being marooned in a pod on a hostile deserted landscape but with your lights and radars still blinking, still whirring, powered by adrenaline and restlessness. It was a short, sharp fear, in anticipation of a crisis that would be intense but soon over.

After many delays, Hubble’s successor is set to travel to a cosmic parking spot 1m miles from EarthFinal preparations are under way for the launch of the James Webb space telescope, a landmark observatory built to peer back through space and time to the first stars and galaxies that lit up the universe.Regarded as the successor to Nasa’s Hubble space telescope, the mission is scheduled to blast off at 12.20pm UK time on Christmas Eve onboard an Ariane 5 rocket from Europe’s spaceport in Kourou, French Guiana. More than 30 years in the making, the telescope is bound for a parking spot in space 1m miles from Earth. Continue reading...

Even if vaccinations hold back the tide of infections, there will still be too many patients for us to look after

Yusaku Maezawa spent 12 days at the space station, marking Russia’s return to space tourism after a decade-long pauseA Japanese billionaire has returned to Earth after 12 days spent on the International Space Station, where he made videos about performing mundane tasks in space including brushing his teeth and going to the toilet.Online fashion tycoon Yusaku Maezawa and his assistant Yozo Hirano parachuted on to Kazakhstan’s steppe at around the expected landing time of 03.13 GMT on Monday, along with Russian cosmonaut Alexander Misurkin, Russia’s space agency said. Continue reading...

Māori boy who died last week was youngest New Zealander to die with virus and the first child

Latest UK daily cases show a 72% jump on the 48,071 new infections recorded last Sunday; Irish officials say 52% of cases estimated to be new variant

Like countless other new parents, Sara had sailed straight into the ‘iceberg’ of unrealistically high expectations

Analysis: Omicron studies so far have been rapid first takes, but the message for England is loud and clear

Thousands drive miles as appointment-only systems jeopardise aim of offering third vaccination to all adults by end of month

While my husband and two children celebrate Christmas without me, I will be rowing 3,000 miles across the AtlanticFor the past few weeks, I’ve been getting ready for Christmas. As well as putting the tree up ridiculously early, I’ve made the cake, bought the presents and assembled the stockings. Even though my children no longer believe in Santa, the crinkle of my dad’s old golf socks stuffed full of presents on Christmas morning still makes their faces light up.But this year, for the first time since they were born, I won’t be there to celebrate with them. I’m leaving my husband Fred, daughter Inès, 15, and son Vincent, 12, to row 3,000 miles across the Atlantic as part of the annual Talisker Whisky Atlantic Challenge. My four-woman crew of mothers is called the Mothership, and between us we have 11 children, the youngest of whom is four. Continue reading...

City project that used lateral flow tests to monitor population took pressure off NHS at critical time

Billionaires in space, an end-date for deforestation, facing up to racial bias in healthcare – we asked scientists to share the most important developments of 2021Space made the headlines on many occasions in 2021: the landing of Nasa’s Perseverance rover on Mars, the arrival of a rare meteorite in the UK, the launch of a mission to hit an asteroid, the discovery of almost 200 new planets beyond the solar system – all shared their moment of fame with the public. However, the most extensive coverage of space news was probably of the 11-minute flight to outside the edge of Earth’s atmosphere made by William Shatner, AKA Captain James T Kirk of the USS Enterprise, in October 2021. Continue reading...

Health workers at King’s College hospital fear a surge in admissions as the Omicron wave gathers force, but are cautiously optimisticOn the third floor of one of the country’s biggest hospital trusts, a team of intensive care specialists in masks and visors huddle around a screened bay where a critically ill patient lies unconscious surrounded by cables and tubes.The elderly man’s breathing is supported by a ventilator and he is connected to an arterial line to measure blood pressure. He is fed by a gastric tube, and a nearby stack of six monitors provide updates on his condition, from oxygen levels to heart rate. Continue reading...

Charities ask for more government help and blame confusion over access to care, shortage of boosters and lack of shielding support

The instrument will be the largest and most powerful telescope ever to be launched into spaceThe much-delayed launch of the James Webb space telescope will go ahead on 24 December, Nasa and the company overseeing the launch have confirmed.The project, begun in 1989, was originally expected to deploy the instrument – which will be the largest and most powerful telescope ever to be launched into space – in the early 2000s. Continue reading...

Deaths could hit 6,000 a day and delaying restrictions until New Year will cut effectiveness, say Sage expertsRead more: is there any good news at all on Omicron?The scale of the threat posed by the Omicron variant was laid bare by government scientists last night as they warned that there are now hundreds of thousands of infections every day. That daily number could reach between 600,000 and 2 million by the end of the month if new restrictions are not brought in immediately.The government’s SPI-M-O group of scientists, which reports to the Scientific Advisory Group for Emergencies (Sage), also warned that, based on their modelling, hospitalisations could peak between 3,000 and 10,000 a day and deaths at between 600 and 6,000 a day. Continue reading...

As part of a Guardian series about chronic pain and long Covid, Linda Geddes explores the growing realisation that pain can be a disease in and of itself. Gabrielle Jackson, associate editor of audio and visual, introduces this storyYou can read the original article here: Sufferers of chronic pain have long been told it’s all in their head. We now know that’s wrongYou can also read and watch more from our series about chronic pain here: The pain that can’t be seen Continue reading...

From a humble garage to international backing, Space Forge plans to manufacture alloys, medicines and semiconductors in microgravityLast year, when Josh Western and Andrew Bacon set up their company Space Forge, they had a garage to work in and little else. Today, the two Cardiff-based entrepreneurs have a staff of 25 and are now planning further expansion after raising £7.6m of international seed-funding.The financing – to be announced later this week – should allow the company to start a remarkable aerospace endeavour: deploying satellites in which new alloys, medicines and semiconductors can be manufactured in outer space and then brought back to Earth. The first missions are now planned for the end of 2022. Continue reading...

Analysis: scientists are only starting to understand new Covid mutation but there is encouraging news from the laboratory, South Africa and on antiviral drugs

Tom Hollander made us laugh at the hypocrisy of religion, but also showed us human kindness