The San Francisco 49ers likely will be without rookie running back Isaac Guerendo for Sunday's game against the Miami Dolphins.

The article in TheAthletic.com that complicates the Jets' effort to hire a high-end G.M. and coach contains plenty of interesting nuggets.

Here's a look at Week 16 of the NFL season from a betting perspective.

Former San Francisco 49ers cornerback Ambry Thomas now will have to wait for another team to claim him.

All games, picked straight up and ATS.

Dominate your Week 16 matchups with all of our fantasy football content, all in one place!

Beware of these six players with bust potential in Week 16!

Jalen Hurts is enjoying the finest stretch of his NFL career and Doug Nussmeier, Eagles' quarterbacks coach, has a lot to do with it.

The 49ers have gotten used to being shorthanded at running back this season and it looks like they'll be down another one in Miami on Sunday.

Several key players have us scratching our heads this week. Fantasy football analyst Tera Roberts makes a call.

Dalton Del Don examines some of the most deceiving fantasy stats through 15 weeks of the season ... including Brian Thomas Jr.'s WR16 rank.

The New York Jets' rocky 2024 campaign has been shaped by unorthodox decision-making, including owner Woody Johnson reportedly relying on Madden NFL video game ratings to evaluate players. According to the Athletic, Johnson vetoed a trade for wide receiver Jerry Jeudy last offseason, citing the player's low Madden rating. Jeudy was later dealt to the Cleveland Browns, where he has thrived with 1,052 receiving yards, ranking fifth in the NFL.

The Dolphins designated edge rusher Bradley Chubb for return a little more than two weeks ago, but he has not been added to the active roster yet.

Colts center Ryan Kelly has played with offensive tackle Braden Smith since the latter was selected in the second round of the 2018 draft.

Many fantasy football managers still need to dig deep, even in the playoff semifinals. Scott Pianowski is here to help.

Each year, some previously un-hyped player emerges from the depths of a roster and makes a surprise fantasy impact. Who will do it this season?

Take another step toward a trip to the fantasy championship with Sal Vetri's favorite RB matchups in Week 16!

Thursday Night Football continues on Prime Video tonight with the Denver Broncos visiting the Los Angeles Chargers. Here's everything you need to know about how to watch tonight's game.

The Broncos and the Chargers kick off Week 16 with their playoff hopes (and those of fantasy football managers) on the line.

Using Madden ratings to judge players is just one example of how Jets owner Woody Johnson is continually hobbling his own team.

The Falcons have elected to bench Kirk Cousins for rookie Michael Penix Jr. while still alive in the postseason race with just three weeks left in the season.

The Chargers offense is set to get a little reinforcement for Thursday night's game against the Broncos.

For most of Travis Kelce's career, the Chiefs have known that if they got him the ball, he was good for about 12 or 13 yards: From Kelce's first season as the Chiefs' starting tight end in 2014 through 2022, Kelce averaged somewhere between 12.2 and 13.5 yards per catch every year.

It has been a miserable season for the Giants as a team, but wide receiver Malik Nabers has a chance to earn some individual glory in the final weeks of the year.

Here are some key matchups to watch as the Eagles face the Commanders in Week 16 at Northwest Stadium.

Everything you need to know about the Chargers facing the Denver Broncos on Thursday at SoFi Stadium, including start time, TV channel and betting odds.

NFL Week 16 picks: Broncos-Chargers matchup Thursday kicks off key divisional rivalries that could determine playoff opponents ... and who might miss out.

The Chargers had to regroup quickly after the NFL moved up their key AFC West game against the Broncos to Thursday, a short week Denver already experienced.

The Rams' Matthew Stafford and the Jets' Aaron Rodgers faced each other many times when they were NFC North rivals and Rodgers currently holds a 13-4 advantage.

Brought to Minnesota to be a bridge to the next generation, Sam Darnold is now leading one of the hottest teams in the league and the potential No 1 seed in the NFC. Yes, really!

Harris dropped a lateral from Wilson on Sunday against the Eagles. It was Harris's fault, but officially Wilson's fumble.

UNLV dual-threat quarterback Hajj-Malik Williams and a consistent defensive effort helped the Rebels earn a 24-13 LA Bowl win over Cal on Wednesday.

UNLV posted a 52-yard gain on a play the defense didn't see coming.

Tom E. Curran and Mike Giardi compare Drake Maye and Josh Allen and explain why the Patriots rookie has the potential to join the Bills QB among the best quarterbacks in the league.

The No. 8 overall pick has played only 20 snaps this season.

What does Bills QB Josh Allen think of Drake Maye's rookie season with the Patriots? Check out what he told reporters Wednesday.

There's a pretty straightforward scenario in which Cousins can join the Browns this upcoming offseason, and it'd be good for both parties. It also won't be easy, but with this QB and this franchise, what has been lately?

Former Patriots QB Brian Hoyer breaks down Drake Maye's shovel-pass touchdown to DeMario "Pop" Douglas in Sunday's loss to the Cardinals.

As the Buccaneers try to get closer to a division title, their most important player is banged up.

Not the best timing for the Commanders.

Dolphins quarterback Tua Tagovailoa has avoided suffering a concussion since returning from the Week 2 injury that caused him to miss four games.

On Sunday, the Seahawks finish their regular-season home schedule with a visit from the Vikings.

The Cardinals designated their kicker, Matt Prater, to return from injured reserve Wednesday.

Kyle Shanahan admitted that Trent Williams isn't recovering from an ankle injury at the rate the San Francisco 49ers would like.

Former San Francisco 49ers cornerback Ambry Thomas has found a new home.

The Colts claimed cornerback Ambry Thomas off waivers Wednesday, the team announced.

Eagles quarterback Jalen Hurts remained a full participant at practice despite a fractured left ring finger.

Here's the full injury report as the Eagles get ready for the Commanders in Week 16.

The Steelers made a significant change to their injury report on Wednesday.

The 49ers have suspended linebacker De'Vondre Campbell for the rest of the season after he refused to play on Thursday night, and coach Kyle Shanahan is acknowledging that in hindsight he wishes he'd never brought Campbell to San Francisco in the first place.