Gene-Edited Animals Can Act as "Surrogate Sires"
takyon writes:
Gene editing to produce 'super dad' livestock
Scientists have produced gene-edited animals they say could serve as "super dads" or "surrogate sires". The pigs, goats, cattle and mice make sperm carrying the genetic material of donor animals.
The researchers used a hi-tech gene editing tool to knock out a male fertility gene in animal embryos. The animals were born sterile, but began producing sperm after an injection of sperm-producing cells from donor animals.
The technique would enable surrogate males to sire offspring carrying the genetic material of valuable elite animals such as prize bulls, said a US-UK team. This would be a step towards genetically enhancing livestock to improve food production, they added.
Also at Reuters and Genetic Engineering and Biotechnology News.
Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males (open, DOI: 10.1073/pnas.2010102117) (DX)
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