50 New Genes for Eye Colour
upstart writes in with an IRC submission:
Eye color genetics not so simple, study finds:
An international team of researchers led by King's College London and Erasmus University Medical Center Rotterdam have identified 50 new genes for eye colour in the largest genetic study of its kind to date. The study, published today in Science Advances, involved the genetic analysis of almost 195,000 people across Europe and Asia.
These findings will help to improve the understanding of eye diseases such as pigmentary glaucoma and ocular albinism, where eye pigment levels play a role.
In addition, the team found that eye colour in Asians with different shades of brown is genetically similar to eye colour in Europeans ranging from dark brown to light blue.
This study builds on previous research in which scientists had identified a dozen genes linked to eye colour, believing there to be many more. Previously, scientists thought that variation in eye colour was controlled by one or two genes only, with brown eyes dominant over blue eyes.
[...] "This study delivers the genetic knowledge needed to improve eye colour prediction from DNA as already applied in anthropological and forensic studies, but with limited accuracy for the non-brown and non-blue eye colours."
Journal Reference:
Mark Simcoe, Ana Valdes, Fan Liu, et al. Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color [open], Science Advances (DOI: 10.1126/sciadv.abd1239)
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