Breakthrough Infection Study Compares Decline in COVID Vaccine Effectiveness: Pfizer v Moderna v J&J
[Ed note: This story combines reports from two separate articles. In the first report are results comparing the likelihood of being infected (and surviving) after having one of the three vaccines that are commonly available in the US. The second report compares the risk of death that results from being infected subsequent to being vaccinated (from the same set of three commonly-available vaccines). No vaccine is perfect; get your booster when it is available; wear a mask in public indoor spaces; and get tested regularly. The life you save may be that of a family member, loved-one, or co-worker! Emphasis retained from originals.--martyb]
upstart writes:
Study in Science of more than 780,000 Veterans is the first to compare waning protection rates across all three vaccine types available to most Americans and to directly report death rates after breakthrough infection.
A new study in the leading journal Science reviewed COVID-19 breakthrough infections among 780,225 Veterans, finding that vaccine protection declined from 87.9% to 48.1% during the 2021 Delta surge in the U.S. The researchers from PHI, the Veterans Affairs Medical Center and the University of Texas Health Science Center found a dramatic decline in effectiveness for the Janssen (Johnson and Johnson) vaccine, from 86.4% in March to 13%.1 in September. They also found that vaccination of any type was protective against death among infected individuals.
As COVID-19 breakthrough infections continue to emerge in some vaccine recipients and health authorities are developing policies around booster vaccinations, national data on COVID-19 vaccine breakthrough infections is inadequate but urgently needed. Now a study from the Public Health Institute, the Veterans Affairs Medical Center and the University of Texas Health Science Center published today in the journal Science analyzed COVID infection by vaccination status among 780,225 Veterans.
Researchers found that protection against any COVID-19 infection declined for all vaccine types, with overall vaccine protection declining from 87.9% in February to 48.1% by October 2021.
- The decline was greatest for the Janssen (Johnson & Johnson) vaccine, with protection against infection declining from 86.4% in March to 13%.1 in September
- Declines for PfizerBioNTech were from 86.9% to 43.3%
- Declines for Moderna were 89.2% to 58%.
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