Article 5TBX5 New Graphene-Based Neural Probes Improve Detection Of Epileptic Brain Signals

New Graphene-Based Neural Probes Improve Detection Of Epileptic Brain Signals

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mrpg
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Arthur T Knackerbracket has processed the following story:

[...] The flexible gDNP [graphene depth neural probe] devices were chronically implanted in mice with epilepsy. The implanted devices provided outstanding spatial resolution and very rich wide bandwidth recording of epileptic brain signals over weeks. In addition, extensive chronic biocompatibility tests confirmed no significant tissue damage and neuro-inflammation, attributed to the biocompatibility of the used materials, including graphene, and the flexible nature of the gDNP device.

The ability to record and map the full range of brain signals using electrophysiological probes will greatly advance our understanding of brain diseases and aid the clinical management of patients with diverse neurological disorders. Current technologies are limited in their ability to accurately obtain with high spatial fidelity ultraslow brain signals.

Epilepsy is the most common serious brain disorder worldwide, with up to 30% of people unable to control their seizures using traditional anti-epileptic drugs. For drug-refractory patients, epilepsy surgery may be a viable option. Surgical removal of the area of the brain where the seizures first start can result in seizure freedom; however, the success of surgery relies on accurately identifying the seizure onset zone (SOZ).

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