Even Mild Covid is Linked to Brain Damage Months After Illness, Scans Show

upstart writes:

Even mild Covid is linked to brain damage months after illness, scans show:

During at least the first few months following a coronavirus infection, even mild cases of Covid-19 are associated with subtle tissue damage and accelerated losses in brain regions tied to the sense of smell, as well as a small loss in the brain's overall volume, a new British study finds. Having mild Covid is also associated with a cognitive function deficit.

These are the striking findings of the new study led by University of Oxford investigators, one that leading Covid researchers consider particularly important because it is the first study of the disease's potential impact on the brain that is based on brain scans taken both before and after participants contracted the coronavirus.

"This study design overcomes some of the major limitations of most brain-related studies of Covid-19 to date, which rely on analysis and interpretation at a single time point in people who had Covid-19," said Dr. Serena S. Spudich, a neurologist at the Yale University School of Medicine, who was not involved in the research.

[...] The research, which was published Monday in Nature, also stands out because the lion's share of its participants apparently had mild Covid - by far, the most common outcome of coronavirus infections. Most of the brain-related studies in this field have focused on those with moderate to severe Covid.

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