Diet Control of Isoleucine Increases Healthspan and Lifespan By Up to 33% in Mice
by Brian Wang from NextBigFuture.com on (#6KJQN)
Low-protein diets promote health and longevity in diverse species. Restriction of the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine recapitulates many of these benefits in young C57BL/6J mice. Restriction of dietary isoleucine (IleR) is sufficient to promote metabolic health and is required for many benefits of a low-protein diet in C57BL/6J males. Here, we ...