UK politics: Labour’s Khan has 22-point lead over Tory rival in London mayoral race, poll suggests – as it happened

The London mayor, running for his third term in office, had been warning of a two-horse race'

When Hilary Cass published her review of gender identity services for children, saying medical evidence did not generally justify giving puberty blockers and cross-sex hormones to children, she said the toxity of the debate" around trans children was exceptional, and she said she would like to see the issue discussed in a less polarised way.

But that has not stopped her report becoming a political football. The UK government responded to it with a ministerial statement treating it as a landmark victory in a culture war. In Scotland the Cass report arguably contributed to the downfall of Humza Yousaf, because it was the Rainbow Greens who launched the process to end the SNP/Scottish Greens pact, and they were partly motivated by the SNP government's stance on puberty blockers.

The landmark Cass review is hugely significant for Wales. Regretfully, despite the weight of the findings, we are still yet to see a Labour minister come to the Senedd and give a statement in response.

In the Senedd tomorrow, I look forward to bringing forward a Welsh Conservative debate on the Cass review, and will call on the Labour government to adopt the recommendations of the Cass review.

The Cass review aims to ensure children and young people who are questioning their gender identity or experiencing gender dysphoria, and require support from the NHS, receive a high standard of care that meets their needs and is safe, holistic and effective.

We are committed to improving the gender identity development pathway and the support available for young people in Wales, in line with the commitments in our LGBTQ+ plan.

I'm the first chairman of the 22 who has had to operate it while we've been in government ... And so my view is that that was a mistake to introduce that rule.

I think it's fine to have the party members voting on the leader when you're in opposition. But in a parliamentary system where essentially you could only remain prime minister if you enjoyed the confidence of your party in parliament, it seems to me crazy that we now have different mechanisms ... The Conservative members of parliament can get rid of the leader by voting no confidence, but then the leader is supplied by the party members.