Article 52YVH How Hearing Loss in Old Age Affects the Brain

How Hearing Loss in Old Age Affects the Brain

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How hearing loss in old age affects the brain:

If your hearing deteriorates in old age, the risk of dementia and cognitive decline increases. So far, it hasn't been clear why. A team of neuroscientists at Ruhr-Universitat Bochum (RUB) in Germany examined what happens in the brain when hearing gradually deteriorates: key areas of the brain are reorganized, and this affects memory. The results are published online in the journal "Cerebral Cortex" dated 20 March 2020.

[...] Memory is enabled by a process called synaptic plasticity. In the hippocampus, synaptic plasticity was chronically impaired by progressive hearing loss. The distribution and density of neurotransmitter receptors in sensory and memory regions of the brain also changed constantly. The stronger the hearing impairment, the poorer were both synaptic plasticity and memory ability.

"Our results provide new insights into the putative cause of the relationship between cognitive decline and age-related hearing loss in humans," said Denise Manahan-Vaughan. "We believe that the constant changes in neurotransmitter receptor expression caused by progressive hearing loss create shifting sands at the level of sensory information processing that prevent the hippocampus from working effectively," she adds.

Denise Manahan-Vaughan, Olena Shchyglo, Mirko Feldmann, Daniela Beckmann. Hippocampal Synaptic Plasticity, Spatial Memory, and Neurotransmitter Receptor Expression Are Profoundly Altered by Gradual Loss of Hearing Ability. Cerebral Cortex, 2020; DOI: 10.1093/cercor/bhaa061

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