Africa ‘on the verge’ of resistance to key malaria drugs, Rwanda study warns

Scientists fear erosion of efficacy of treatment has begun, with children at greatest risk

Resistance to malaria drugs in Africa may be starting to take hold, according to a study that maps changes similar to those seen a decade ago when drug resistance spread in south-east Asia.

In Cambodia and neighbouring countries, the artemisinin drug compounds widely used against malaria are no longer always effective. The falciparum malaria parasites have developed genetic mutations that allow them to evade the drugs. There has been great concern that drug resistance could spread to Africa, which has the highest burden of cases of this type of malaria - and the highest toll of child deaths from it.