Article 5QY1F Scientists Partially Restore Vision in Legally Blind People With the Help of CRISPR Gene-Editing

Scientists Partially Restore Vision in Legally Blind People With the Help of CRISPR Gene-Editing

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martyb
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upstart writes:

Scientists partially restore vision in legally blind people with the help of CRISPR Gene- Editing - OnePexel:

Recently Scientists were able to restore vision in legally blind patients through a gene-editing experiment. Many people who were part of this experiment were born with vision issues but are now able to see betterS[sic]

Seven patients volunteered for the experiment, wherein doctors modified their DNA by injecting a gene-editing CRISPR directly into the cells. Researchers revealed on Wednesday that patients with leber congenital amaurosis (LCA), a severe form of vision impairment had their vision improved after the gene-editing therapy.

[...] Scientists had earlier used the tool to remove cells from bodies of patients, taking them to the lab for editing, and then infusing the modified cells into patients.

[...] Unlike gene-editing for other diseases, doctors infused the modified gene into the eye directly instead of in a petri dish. Until now, the patients received the CRISPR treatment only in one eye. The treatment will be extended to the other eye if all things go well.

Even then, the treatment did not repair vision for all. Doctors suspect this is due to insufficient dosage or due to too much vision damage.

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