Study Shows Willow Bark Extract Has Broad-Spectrum Antiviral Effect
taylorvich writes:
https://phys.org/news/2023-11-willow-bark-broad-spectrum-antiviral-effect.html
From a seasonal cold to a stomach bug, nobody likes catching a virus-and epidemics can be devastating. We need safe, sustainable antiviral options to treat the outbreaks of the future. Scientists in Finland have now shown that an extract of willow bark-a plant that has already provided several medicines, including the precursor to modern aspirin-has a broad-spectrum antiviral effect in cell sample experiments.
The extract worked both on enveloped coronaviruses, which cause colds as well as COVID-19, and non-enveloped enteroviruses, which cause infections such as flu and meningitis. There are no clinically approved drugs that work against enteroviruses directly, so this extract could be a future game-changer.
"We need broadly acting and efficient tools to combat the virus load in our everyday life," said Prof Varpu Marjomaki of the University of Jyvaskyla, senior author of the study in Frontiers in Microbiology. "Vaccinations are important, but they cannot deal with many of the newly emerging serotypes early enough to be effective on their own."
The scientists had previously tested willow bark extract on enteroviruses, and found it was highly successful. In this new study, they expanded the remit of their research to look at additional kinds of virus and to try to understand the mechanism of the extract's action.
To make the extract, they harvested commercially grown willow branches. The bark was cut into pieces, frozen, ground, and then extracted using hot water. This produced the extract samples that the scientists tested against enteroviruses-strains of Coxsackievirus A and B-and coronaviruses-a seasonal coronavirus and COVID-19.
More information: Willow (Salix spp.) bark hot extracts inhibit both enveloped and nonenveloped viruses: study on its anti-coronavirus and anti-enterovirus activities, Frontiers in Microbiology (2023). DOI: 10.3389/fmicb.2023.1249794
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