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Updated 2025-09-15 00:33
New system for therapeutic gene delivery increases transgene expression up to 100-fold
Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector. The ability to increase transgene expression by up to 40 to 100-fold, which would reduce the cost of manufacturing and perhaps also lessen the immune response of AAV/MIP-based gene therapy, is reported in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers
Storing solar power increases energy consumption and emissions
Homes with solar panels do not require on-site storage to reap the biggest economic and environmental benefits of solar energy, according to research from the Cockrell School of Engineering at The University of Texas at Austin. In fact, storing solar energy for nighttime use actually increases both energy consumption and emissions compared with sending excess solar energy directly to the utility grid.
Substantial evidence we live in a vast and complex holographic universe
A UK, Canadian and Italian study has provided what researchers believe is the first observational evidence that our universe could be a vast and complex hologram.
Russia launching its quietest submarine
The fourth Yasen-class submarine, the Krasnoyarsk, has passed critical tests of its structures and pressure hull, according to Russia’s TASS news agency. It’s supposed to be the most quiet nuclear-powered attack sub ever to enter the Russian fleet.
Comparison Review of F-35C and Advanced Super Hornet has been Ordered
Defense Secretary James Mattis is ordering a Pentagon review to compare the capabilities and cost between the emerging carrier-based Lockheed Martin F-35C Lighting II Joint Strike Fighter and an upgraded version of the Boeing F/A-18 E/F Super Hornet, according to a memo obtained by USNI News.
5 Xprize teams are launching to the moon this year
Five finalist teams in the Google Lunar XPRIZE have been set, and they all have rocket launch contracts to go to the Moon in 2017.
John Hurt died. He was famous for having chest burst by Alien and as Doctor Who during Dalek Time War
John Hurt, who died on Friday, was a brilliant and versatile actor who made memorable film appearances over five decades.
Organovo bioprinting human tissue for drug testing and within 6 years for implanting human livers
Organovo designs and create functional human tissues using our proprietary three-dimensional bioprinting technology. Their goal is to build living human tissues that are proven to function like native tissues. With reproducible 3D tissues that accurately represent human biology, they are enabling ground-breaking therapies by:
Printed human body parts could be available for human transplants within a few years
Every year about 120,000 organs, mostly kidneys, are transplanted from one human being to another. Sometimes the donor is a living volunteer. Usually, though, he or she is the victim of an accident, stroke, heart attack or similar sudden event that has terminated the life of an otherwise healthy individual. But a lack of suitable donors, particularly as cars get safer and first-aid becomes more effective, means the supply of such organs is limited. Many people therefore die waiting for a transplant. That has led researchers to study the question of how to build organs from scratch.
Tsunami prevention with massic deep ocean sound waves
Devastating tsunamis could be halted before hitting the Earth’s shoreline by firing deep-ocean sound waves at the oncoming mass of water, new research has proposed.
Medical first,children had cancer cured with genetically engineered T-cells from another person
Doctors in London say they have cured two babies of leukemia in the world’s first attempt to treat cancer with genetically engineered immune cells from a donor.
NASA has new test for life on other planets that is ten thousand times more sensitive
A simple chemistry method could vastly enhance how scientists search for signs of life on other planets.
CRISPR genome engineering research institute expands into agriculture, microbiology
An initiative launched two years ago by UC Berkeley and UC San Francisco to use CRISPR-Cas9 gene editing to develop new disease therapies is expanding into research on the planet’s major crops and poorly understood microbiomes, with plans to invest $125 million in these areas over the next five years.
Scientists unveil new form of matter: time crystals
most people, crystals mean diamond bling, semiprecious gems or perhaps the jagged amethyst or quartz crystals beloved by collectors.
Two Bellafonte nuclear plants could be completed by 2028 with $13 billion investment
The future development of Bellefonte Nuclear Plant, the northeast Alabama facility sold at auction in November, will generate an economic impact of $1 billion and provide more than 12,000 jobs.
New Spacesuit Unveiled for Starliner Astronauts
Astronauts heading into orbit aboard Boeing’s Starliner spacecraft will wear lighter and more comfortable spacesuits than earlier versions. The suit capitalizes on historical designs, meets NASA requirements for safety and functionality, while introducing cutting-edge innovations. Boeing unveiled its spacesuit design Wednesday as the company continues to move toward flight tests of its Starliner spacecraft and launch systems that will fly astronauts to the International Space Station.
US Navy will fire 150 kilowatt laser on a test ship in 2018 and then from carriers and destroyers in 2019
The U.S. Navy is moving at warp speed to develop lasers with more lethality, precision and power sources as a way to destroy attacking missiles, drones aircraft and other threats.
DWave next redesign will allow for higher connection density 4000 qubits by late 2018 and expansion beyond 10,000 qubits
D-Wave is also working on a fifth model, which will provide even greater capacity and connectivity and a closer fit to scientists’ needs. It will likely to launch within two years, the machine will again double the number of qubits, to around 4,000. Crucially, it will also provide more-complex connections between qubits, allowing it to tackle more-complicated problems.
Ukraine and China progressing on making super heavy helicopter with 30 ton capacity
Ukraine has test fired for the first time newly designed engine AI-136T. It is intended for China's super heavy helicopter program. The helicopter itself is planned to be based on Soviet MI-26 airframe design, although scaled down somewhat to a smaller size. In combination with more powerful engine than previously used, new helicopter is expected to be a much more energetic machine, with higher combat ceiling, higher speed and better maneuverability. Expected payload capacity is 30 tons.
Robotic Fabricator Can precisely lay brick and weld wire and next generation bot will be stronger and lighter
A construction robot has to be powerful enough to handle heavy material, small enough to enter standard buildings, and flexible enough to navigate the terrain.
Automation speeds clinical safety surveillance
Using patient outcomes data from approximately 1,800 hospitals, the largest demonstration to date of automated safety surveillance of a medical device is reported in this week's New England Journal of Medicine.
Deep Learning algorithm will enable 6.3 billion cellphones in 2021 to diagnose skin cancer matching Dermatologist performance
Computer scientists at Stanford set out to create an artificially intelligent diagnosis algorithm for skin cancer. They made a database of nearly 130,000 skin disease images and trained their algorithm to visually diagnose potential cancer. From the very first test, it performed with inspiring accuracy.
US Navy Sticking With Advanced Arresting Gear in Next Carrier despite tripling cost from $476 million to $1.4 billion
The Navy is electing to use the controversial Advanced Arresting Gear on its next Gerald R. Ford-class carrier, John F. Kennedy (CVN-79), USNI News has learned.
Elon Musk will start making traffic busting tunnels next month
Elon Musk thinks being stuck in traffic is “soul-destroying” — but, he has a solution: tunnels. Musk has been tweeting about tunnels for a month now, and even said he’s going to build a tunnel boring machine and start digging. In developed cities, we can’t widen roadways, and elevated highways are ugly. So, we dig.
How Many Gigafactories to provide batteries to offgrid electricity to 1.2 billion people without electricity ?
The Tesla Gigafactory will significantly add to the world supple of lithium batteries.
Physicists patent detonation technique to mass-produce graphene
A Kansas State University team of physicists has discovered a way to mass-produce graphene with three ingredients: hydrocarbon gas, oxygen and a spark plug.
Dwave adiabatic quantum system can factor numbers up to 200,000 and a lot larger likely in the 40 bit range
There are adiabatic factoring algorithms and methods.
Terrestrial Energy notifies nuclear regulator of planned 2019 molten salt reactor licensing application
Terrestrial Energy USA announced today it had informed the US Nuclear Regulatory Commission (NRC) of its plans to license a small modular reactor (SMR) in the USA. Terrestrial said it intends to start "pre-application interactions" with the regulator this year and to make its licensing application in late 2019.
High Frequency Financial Traders can now have 20 nanosecond latency down from 200 nanoseconds
In high frequency trading, the latency gold standard is 200 nanoseconds. If you’re an equity trader using a Bloomberg Terminal or Thomson Reuters Eikon, latency of more than 200 nanoseconds is considered to be shockingly pedestrian, putting you at risk of buying or selling a stock at a higher or lower price than the one you saw quoted. Now, with its announcement of TCPDirect, Solarflare said it has cut latency by 10X, to 20-30 nanoseconds.
Carnival of Space 492
The Carnival of Space 492 is up at Urban Astronomer
Survivalism for the rich and famous
Survivalism, the practice of preparing for the collapse of civilization, tends to evoke a certain picture: the woodsman in the tinfoil hat, the hysteric with the hoard of beans, the religious doomsayer. But in recent years survivalism has expanded to more affluent quarters, taking root in Silicon Valley and New York City, among technology executives, hedge-fund managers, and others in their economic cohort.
Fewer high paying oil rig jobs because of robots and process improvement
The robot on an oil drillship in the Gulf of Mexico made it easier for Mark Rodgers to do his job stringing together heavy, dirty pipes. It could also be a reason he’s not working there today.
DWave Systems 2000 qubit adiabatic quantum computing system is now generally commercially available
D-Wave Systems Inc., the leader in quantum computing systems and software, today announced general commercial availability of the D-Wave 2000Q quantum computer. D-Wave also announced the first customer for the new system, Temporal Defense Systems Inc. (TDS), a cutting-edge cyber security firm. With 2000 qubits and new control features, the D-Wave 2000Q system can solve larger problems than was previously possible, with faster performance, providing a big step toward production applications in optimization, cybersecurity, machine learning, and sampling.
Near term off-grid electrification for 1.2 billion people and enabling the extremely poor to reach future purchasing global middle class
Solar energy prices have been dropping for decades. There is a lag in the price per watt of off grid solar for solar home systems behind the cost for solar per watt for the most efficient utility solar projects.
Future hunger risks will be reduced with progress eliminating extreme poverty and improved crops
Achieving the transformation to sustainable agriculture is a major challenge. Changes will need to be made in a way that does not jeopardize the capacity of the agriculture sectors crops, livestock, fisheries and forestry – to meet the world’s food needs. Global food demand in 2050 is projected to increase by at least 60 percent above 2006 levels, driven by population and income growth, as well as rapid urbanization. In the coming decades, population increases will be concentrated in regions with the highest prevalence of undernourishment and high vulnerability to the impacts of climate change.
Achieving Zero Hunger
Eradicating world hunger sustainably by 2030 will require an estimated additional $267 billion per year on average for investments in rural and urban areas and in social protection, so poor people have access to food and can improve their livelihoods, a new UN report says. This would average $160 annually for each person living in extreme poverty over the 15 year period.
A leap in affordability and power to weight ratio with Fabric Pneumatic Exoskeleton Technology
Roam Robotics wants to create light and affordable exoskeletons that will be usable by a lot of people for everyday use.
Semiconductor for next generation power electronics
Researchers have demonstrated the high-performance potential of an experimental transistor made of a semiconductor called beta gallium oxide, which could bring new ultra-efficient switches for applications such as the power grid, military ships and aircraft.
Astronomer searches for signs of life on Wolf 1061 exoplanet
SF State astronomer Stephen Kane is searching for signs of life in one of the extrasolar systems closest to Earth.
Improved Artificial Intelligence will allow pilots to control drone wingmen
F-35s, F-22s and other fighter jets will soon use improved “artificial intelligence” to control nearby drone “wingmen” able to carry weapons, test enemy air defenses or perform intelligence, reconnaissance and surveillance missions in high risk areas, senior Air Force officials said.
Star Trek Discovery Show delayed
CBS All Access' Star Trek: Discovery has been delayed again as the series continues casting. The series is set roughly a decade before the events (2258-2260) of the original Star Trek series, the series follows the crew of the USS Discovery as they discover new worlds and civilizations, while exploring the franchise's signature contemporary themes.
Telsa Autopilot 2.0 could be ten times safer than human only driving which could eventually save over 1 million lives per year worldwide
Based on actual first year driving data, Tesla vehicles with first generation Autopilot had a crash rate that was 40% less than regular cars without Autopilot.
Exosuit reduces energy needed to walk by 23%
A new study shows, that in test group of seven healthy wearers, they clearly saw that the more assistance provided to the ankle joints, the more energy the wearers could save with a maximum reduction of almost 23% compared to walking with the exosuit powered-off. This is the highest relative reduction in energy expenditure observed to date with a tethered exoskeleton or exosuit.
Russia is an active but shrinking geopolitical player where the future will be mostly bipolar between USA and China
By the 2030s — Russia may become less dangerous than Iran, which military strategist Andrew Krepinevich forthcoming study from the Center for Strategic and Budgetary Assessments ranks currently at No. 3.
Official America First Energy Plan embraces $50 trillion in uptapped shale oil and gas
The Whitehouse has issued an America First Energy Plan
US will be building missile defenses and 350 ship navy
President Trump has issued a series of official Whitehouse policy statements. "Making Our Military Strong Again" says they will end the defense sequester and submit a new budget to Congress outlining a plan to rebuild our military. We will provide our military leaders with the means to plan for our future defense needs.
Peak Smartphones is near
Smartphones will continue to grow through Gartner’s forecast period, but their share of the semiconductor pie will peak in 2017 at 25.4% and their overall amount of chip revenue will max out at $97.7 billion in 2018 as growth shifts to mid- and low-end models.
Russia will make 400 T90M tanks with Armata upgrades like an autoloaded 125 mm gun
Russia is making an improved T90M variant of the T90 tank which will feature many of the technologies developed for Russia’s revolutionary T-14 Armata. The T-90M will be remanufactured from Russia’s existing fleet of T-90As — will be far less costly than the fearsome, but expensive, Armata.
Tesla production could hit 183,000 cars in 2018 as electric cars start going prime time hitting 15-25% of all cars by 2025
Morgan Stanley said it has increased its expectations for the Tesla Model 3, now saying the launch will take place later this year, and raised its sales forecast for Teslas overall to 183,000 in 2018 from its previous target of 114,000, although this is still 64% lower than the company’s 500,000 ambition for 2018. Morgan Stanley’s overall volume projection for 2020 is about two thirds less than Tesla’s 1 million. It doesn’t expect net profitability under U.S. GAAP rules before 2019 and free cash flow generation until very late 2018.
Star Trek Axanar case is settled so we will only get two 15 minute shorts and not feature length show
Axanar Productions is pleased to announce that we have reached a formal resolution to the lawsuit brought against Alec Peters, and the fan film production, AXANAR, by CBS Studios, Inc. and Paramount Pictures Corporation.
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